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ProteomicsA Phosphoinositide Interacting Protein Coordinates Stress Precursor Activities
Samd14 coordinates stem cell factor/Kit receptor signaling and is crucial for the survivalof red blood cel precursors within anemia contexts. Here we present new findings that Samd14 expression is needed to maintain balanced autophagy in red blood cell precursors following acute anemia. Autophagy ge...
ORGANISM(S): Anemia Mus musculus (Mouse) 
2026-02-11 | PXD067716 | Pride
Autophagy Samd14 Red blood cells Phosphatidylinositol 3-phosphate 
TranscriptomicsTranscriptional analysis of the effect of Alprostadil on NPHP1 URECs
Micro-array experiment was performed on URECs (Urine-derived Renal Epithelial Cells) from a patient carrying recessive NPHP1 mutation. URECs were treated either with 0.04% of DMSO or 2µM of Alprostadil for 24h.
ORGANISM(S): Homo sapiens 
2022-04-05 | E-MTAB-11582 | biostudies-arrayexpress
MetabolomicsPREDICT: untargeted metabolomic profiling in a Brassica napus (canola) breeding population by GC-MS

Genome-wide association studies (GWAS) identified thousands of genetic loci associated with complex plant traits, including many traits of agronomical importance. However, functional interpretation of GWAS results remains challenging because of large candidate regions due to linkage disequilibriu...

2023-11-20 | MTBLS8056 | MetaboLights
TranscriptomicsTranscriptional analysis of NPHP1 URECs
Bulk RNAseq of URECs (Urine-derived Renal Epithelial Cells) from controls or patients carrying recessive NPHP1 mutations.
ORGANISM(S): Homo sapiens 
2022-04-04 | E-MTAB-11593 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Nphp1-/- KO mouse model kidneys in response to Alprostadil treatment
Bulk RNAseq of kidneys from 5 months-old mice invalidated for Nphp1, which is the main gene responsible for Nephronophtisis, after 4 months of treatment with daily intraperitoneal injection of vehicle of Alprostadil (80µg/kg).
ORGANISM(S): Mus musculus 
2022-04-05 | E-MTAB-11595 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Nphp1-/- KO mouse model kidneys
Bulk RNAseq of kidneys from 5 months-old mice invalidated for Nphp1 which is the main gene responsible for Nephronophtisis, a genetic kidney disease
ORGANISM(S): Mus musculus 
2022-04-04 | E-MTAB-11594 | biostudies-arrayexpress
UnknownColchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.
Not available
S-EPMC8159193 | biostudies-literature
TranscriptomicsGene expression profiling of hypertensive and hypotensive mice
Hypertension is a condition with major cardiovascular and renal complications, affecting nearly a billion patients worldwide. Few validated gene targets are available for pharmacological intervention, so there is a need to identify new biological pathways regulating blood pressure and containing nov...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-19817 | biostudies-arrayexpress
UnknownDetection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.
Not available
S-EPMC7724284 | biostudies-literature
UnknownProminent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes.
Not available
S-EPMC12795280 | biostudies-literature
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