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To examine the molecular mechanisms by which RPA1 regulates transcription in liver, we conducted immunoprecipitation followed by mass spectrometry to characterize RPA1-associated proteins in mouse liver.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-19 | PXD021529 | Pride
Serratia marcescens RPA1 Genome sequencing and assembly
The role of RPA1 in T cell
The role of RPA1 in T cells [thymus]
The role of RPA1 in T cells [spleen]
Lysine crotonylation (Kcr) is a recently-identified protein short-chain acylation. We have previously reported that chromodomain Y-like transcription corepressor CDYL acts as a crotonyl-CoA hydratase and negatively regulates histone Kcr. However, the global crotonylome of CDYL-regulated Kcr on non-h...
ORGANISM(S): Homo sapiens (Human) 
2020-04-02 | PXD013616 | Pride
Transcription factor access to regulatory elements is prevented by the nucleosome. Heat shock factor 1 (HSF1) is a winged helix transcription factor that plays roles in control and stressed conditions by gaining access to target elements, but mechanisms of HSF1 access have not been well known in mam...
ORGANISM(S): Mus musculus 
RPA1 Remodels Liver Chromatin Architecture to Maintain Lipid Metabolic Homeostasis
As a single strand DNA binding protein, RPA1 participates various cellular processes including DNA replication and DNA repair.However, the role of RPA1 in T cell is largely unknown. We generate a mice model in which RPA1 was specifically deleted in T cell. Through single cell RNA sequencing, we reve...
ORGANISM(S): Mus musculus 
2024-06-15 | GSE189548 | GEO
As a single strand DNA binding protein, RPA1 participates in various cellular processes including DNA replication and DNA repair. However, the role of RPA1 in T cells is largely unknown. We generated a mouse model in which RPA1 was specifically deleted in T cells. Through single cell RNA sequencing,...
ORGANISM(S): Mus musculus 
2024-06-15 | GSE189929 | GEO
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