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GenomicsRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-seq]
RPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-seq]
PRJNA797177 | ENA
GenomicsRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [TT-seq]
RPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [TT-seq]
PRJNA793177 | ENA
GenomicsRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-Rx]
RPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-Rx]
PRJNA797176 | ENA
OtherRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [TT-seq]
RNA polymerase II (Pol II)-mediated transcription in metazoan requires precise regulation. RNA polymerase II-associated protein 2 (RPAP2) was previously identified to transport Pol II from cytoplasm to nucleus and dephosphorylates Pol II C-terminal domain (CTD). We found that RPAP2 binds hypo/hyper-...
ORGANISM(S): Homo sapiens 
2022-05-04 | GSE192782 | GEO
GenomicsRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-Rx]
RNA polymerase II (Pol II)-mediated transcription in metazoan requires precise regulation. RNA polymerase II-associated protein 2 (RPAP2) was previously identified to transport Pol II from cytoplasm to nucleus and dephosphorylates Pol II C-terminal domain (CTD). We found that RPAP2 binds hypo/hyper-...
ORGANISM(S): Homo sapiens 
2022-05-04 | GSE193678 | GEO
GenomicsRPAP2 regulates a transcription initiation checkpoint by prohibiting assembly of preinitiation complex [ChIP-seq]
RNA polymerase II (Pol II)-mediated transcription in metazoan requires precise regulation. RNA polymerase II-associated protein 2 (RPAP2) was previously identified to transport Pol II from cytoplasm to nucleus and dephosphorylates Pol II C-terminal domain (CTD). We found that RPAP2 binds hypo/hyper-...
ORGANISM(S): Homo sapiens 
2022-05-04 | GSE193679 | GEO
UnknownCryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2.
Not available
S-EPMC8140126 | biostudies-literature
UnknownSer7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes.
Not available
S-EPMC3262128 | biostudies-literature
ProteomicsStructure of cytoplasmic RNA polymerase II
Before RNA polymerase II (Pol II) can enter the nucleus, where it transcribes messenger RNA, it must first be assembled in the cytoplasm. We have performed proteomic and structural analysis of endogenous human cytoplasmic Pol II complexes, enriched in known biogenesis factors including RPAP2 and the...
ORGANISM(S): Homo sapiens (Human) 
2026-07-14 | PXD070852 | Pride
Rpap2 Xl-ms Gpn1. gpn3 Gdown1 Rna polymerase ii 
UnknownTGFβ1 regulates HRas-mediated activation of IRE1α through the PERK-RPAP2 axis in keratinocytes.
Not available
S-EPMC9486931 | biostudies-literature
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