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Transcriptomic analysis of androgen responsive LNCaP cells depleted (RPS6KB1 KO), overexpressing for RPS6KB1 (RPS6KB1 OE) and treated with berberine (24h treatment with 5 microg/ml prior to radiation) in combination with radiation. Results provide insight into the role of RPS6KB1 in response to radi...
ORGANISM(S): Homo sapiens 
2025-06-04 | GSE245798 | GEO
Evaluate of transcriptomic alternation with Berberine and RPS6KB1 depletion that sensitizes prostate tumors to radiation
Knocked-down of P70S6K in zebrafish (double knockdown of rps6kb1/2) using embryo Cas9/gRNA RNP injections followed by phosphoproteomics of caudal fin.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-12-16 | PXD054212 | Pride
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