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ProteomicsAnalysis of insulin-regulated phosphorylation of AFF4 with Akti or S6ki and S6K invitro kinase
Aff4 was recently identified as an insulin-regulated phosphoprotein. To investigate upstream kinases, we analysed immunoprecipitated Aff4 treated with our without insulin and treated with either an Akti or a P70S6Ki. These results showed that AFF4 is dependent on P70S6K and therefore an in vitro kin...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-16 | PXD054247 | Pride
Akt P70s6k Phosphorylation Aff4 
ProteomicsZebrafish caudal fin phosphoproteomic of Rps6kb1a/b knockdown
Knocked-down of P70S6K in zebrafish (double knockdown of rps6kb1/2) using embryo Cas9/gRNA RNP injections followed by phosphoproteomics of caudal fin.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-12-16 | PXD054212 | Pride
Phosphoproteomics P70s6k Rps6kb1 Zebrafish 
UnknownDeciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer.
Not available
S-EPMC2496917 | biostudies-literature
Genomics
RNA sequencing of SH-SY5Y cells after Abeta 42 treatment and p70S6K knockdown
PRJNA1128853 | ENA
UnknownNon-canonical Raf-1/p70S6K signalling in non-small-cell lung cancer.
Not available
S-EPMC6815804 | biostudies-literature
UnknownThe p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth.
Not available
S-EPMC4714881 | biostudies-literature
Unknownp70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy.
Not available
S-EPMC4508348 | biostudies-literature
UnknownB3galt5 deficiency attenuates hepatocellular carcinoma by suppressing mTOR/p70s6k-mediated glycolysis.
Not available
S-EPMC11072394 | biostudies-literature
UnknownTargeting GPCR-mediated p70S6K activity may improve head and neck cancer response to cetuximab.
Not available
S-EPMC3149755 | biostudies-literature
UnknownMECP2 Mutation Interrupts Nucleolin-mTOR-P70S6K Signaling in Rett Syndrome Patients.
Not available
S-EPMC6305968 | biostudies-literature
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