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TranscriptomicsWhole blood RNA-seq data of SPMS vs RRMS patients from paper titled \"Relapsing remitting and secondary progressive multiple sclerosis are characterised by distinct metabolomic and transcriptomic signatures that could aid patient management strategies\\
We combined analysis of serum metabolomics and whole blood transcriptomics in patients with RRMS and SPMS to build an integrated network describing these different phases of MS and to help improve our understanding of the potential mechanisms driving disease progression. Transcriptomic analysis of...
ORGANISM(S): Homo sapiens 
2024-09-19 | E-MTAB-13378 | biostudies-arrayexpress
TranscriptomicsDefective structural RNA processing in relapsing-remitting multiple sclerosis
It is fundamentally unknown how normal cellular processes or responses to extracellular stimuli may invoke polyadenylation and degradation of ncRNA substrates or if human disease processes exhibit defects in polyadenylation of ncRNA substrates as part of their pathogenesis. Our results demonstrate t...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-GEOD-66573 | biostudies-arrayexpress
ProteomicsProteomics of RRMS plasma samples
Quantitative proteomics of plasma samples from relapse-remitting multiple sclerosis (RRMS) patients
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD057428 | Pride
Rrms Proteomics Mass spectrometry Plasma Multiple sclerosis 
TranscriptomicsMultiple sclerosis patient-derived CSF induces transcriptional changes in proliferating oligodendrocyte progenitors
This study provides an overview of the transcriptional signature of oligodendrocyte progenitor cells (OPCs) exposed to the CSF collected from multiple sclerosis patients with either a relapsing remitting disease course (RRMS) or a confirmed primary progressive diagnosis (PPMS). Using an Affymetrix ...
ORGANISM(S): Rattus norvegicus 
2015-06-19 | E-GEOD-60881 | biostudies-arrayexpress
GenomicsSingle-nucleus RNA sequencing analysis of normal-appearing brains from RRMS and SPMS patients
Single-nucleus RNA sequencing analysis of normal-appearing brains from RRMS and SPMS patients
PRJNA744238 | ENA
UnknownTh17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only.
Not available
S-EPMC6990617 | biostudies-literature
GenomicsCLARITY study: Expression data from RRMS patients treated with Oral Cladribine versus Placebo at week 96
CLARITY study: Expression data from RRMS patients treated with Oral Cladribine versus Placebo at week 96
PRJNA770732 | ENA
TranscriptomicsSingle-nucleus RNA sequencing analysis of normal-appearing brains from RRMS and SPMS patients
snRNA-seq reveals that normal-appearing brain regions from RRMS and SPMS patients have divergent cell type-specific gene expression profiles, with clinical ramifications for approved sphingosine 1-phosphate (S1P) receptor modulators.
ORGANISM(S): Homo sapiens 
2022-01-06 | GSE179590 | GEO
Genomicssynthetic construct
hnRNP A1 RRMs specifically binding RNA motif
PRJNA298392 | ENA
UnknownDistributed causality in resting-state network connectivity in the acute and remitting phases of RRMS.
Not available
S-EPMC7493168 | biostudies-literature
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