Biogenesis of eukaryotic box C/D snoRNPs initiates co-transcriptionally and requires the action of an assembly machinery including the HSP90/R2TP complex, Rsa1p:Hit1p (NUFIP1:ZNHIT3 in human) heterodimer and the Bcd1 protein (ZNHIT6 in human). We identified genetic interactions between the Rsa1p-enc...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)