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ProteomicsGermline encoded residues dominate the interaction of a human monoclonal antibody with Decorin binding protein A (DbpA) of Borrelia burgdorferi
During the course of Lyme disease, humans mount a robust and sustained antibody response against dozens of Borrelia burgdorferi outer surface lipoproteins. Identifying which antibodies are associated with spirochete clearance and disease resolution is of paramount importance in therapeutic developme...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD062826 | Pride
Monoclonal Borrelia Dbpa Hdx-ms 
UnknownThe Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B-Cell Subset in Multiple Sclerosis.
Not available
S-EPMC7870993 | biostudies-literature
TranscriptomicsTranscription profiling of acute telomere dysfunction in the mouse liver using adenoviral mediated, transient expression of a dominant negative version of TRF
Telomere dysfunction induces two types of cellular responses: cellular senescence and apoptosis. Here we analyzed the influence of the cellular level of telomere dysfunction and the role of p53 on induction of apoptosis and senescence in mouse liver using the experimental system of adenoviral mediat...
ORGANISM(S): Mus musculus 
2006-11-21 | E-MEXP-141 | biostudies-arrayexpress
UnknownPyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
Not available
S-EPMC4017973 | biostudies-literature
UnknownStructural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Not available
S-EPMC4945499 | biostudies-literature
UnknownSerological Analysis Identifies Consequential B Cell Epitopes on the Flexible Linker and C-Terminus of Decorin Binding Protein A (DbpA) from Borrelia burgdorferi.
Not available
S-EPMC9429923 | biostudies-literature
UnknownA Refined Human Linear B Cell Epitope Map of Outer Surface Protein C (OspC) From the Lyme Disease Spirochete, Borrelia Burgdorferi.
Not available
S-EPMC11867186 | biostudies-literature
UnknownStructural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Not available
S-EPMC10128040 | biostudies-literature
ProteomicsEchovirus-30 Infection Alters Host Proteins in Lipid Rafts at the Cerebrospinal Fluid Barrier In Vitro
Echovirus-30 (E-30) is a non-polio enterovirus responsible for meningitis outbreaks in children worldwide. To gain access to the central nervous system (CNS), E-30 first has to cross the blood-brain barrier (BBB) or the blood-cerebrospinal fluid barrier (BCSFB). E-30 may use lipid rafts of the host ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-29 | MSV000086646 | MassIVE
UnknownA type-specific B-cell epitope at the apex of outer surface protein C (OspC) of the Lyme disease spirochete, <i>Borreliella burgdorferi</i>.
Not available
S-EPMC11960070 | biostudies-literature
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