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TranscriptomicsExpression from early pre-hematopoietic progenitors from mouse embryo
Hematopoietic Stem Cells (HSC) are originated during embryonic development from endothelial-like cells located in the ventral side of the dorsal aorta around day E10-12 of murine development. This region is called AGM for Aorta/Gonad/Mesonephros and refers to the tissues around the hemogenic aorta. ...
ORGANISM(S): Mus musculus 
2012-07-02 | E-GEOD-35395 | biostudies-arrayexpress
ProteomicsProteomic analysis of acute pancreatitis in TRP14-KO miceProteomic analysis of acute pancreatitis in TRP14-KO mice
We have studied pancreas samples in pancreas from a mouse model of acute pancreatitis, comparing wild-type animals and TRP14 KO animals. Samples are extracted with N-ethylmaleimide to block reduced cysteines, and no reducing agent is used, with a search including cysteinylated peptides. Acute pancr...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-15 | PXD050765 | Pride
Mouse model Cysteine Disulfide exchange Pancreatitis Biological redox systems Oxidative stress 
TranscriptomicsRelief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF mutant thyroid carcinomas.
Analysis of transcriptome kinetics of SW1736 thyroid cancer cell line vs SK-MEL-28 melanoma cell line at various times after addition of 2 µM vemurafenib. The hypothesis tested was that SW1736 cells (vemurafenib-refractory) differentially express genes compared to SK-MEL-28 cells (vemurafenib sensit...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-37441 | biostudies-arrayexpress
ProteomicsThe dynamic regulatory genome of Capsaspora owczarzaki and the origin of animal multicellularity
Recent evidence that the unicellular ancestor of animals had a complex repertoire of genes linked to multicellular processes suggests that changes in the regulatory genome, rather than gene innovation, were key to the origin of animals. Here, we carry out multiple functional genomic assays in Capsas...
ORGANISM(S): Capsaspora owczarzaki 
2018-10-24 | PXD002342 | Pride
Histone acetylation methylation dimethilation trimethylation capsaspora owczarzaki 
TranscriptomicsTranscriptomic response of rice leaves to 30% CO2 concentration
Analysis of rice leaves (V2 stage) in response to a short treatment with very high CO2 concentration in the dark, using standard atmosphere as control. Results provide insight into molecular mechanisms occurring in response to these extreme conditions, which are often used in the food industry. V2 r...
ORGANISM(S): Oryza sativa 
2016-07-01 | E-GEOD-70840 | biostudies-arrayexpress
TranscriptomicsThe Rpd3L HDAC complex is essential for the heat stress response in yeast
To ensure cell survival and growth during temperature increase, eukaryotic organisms respond with transcriptional activation that results in accumulation of proteins that protect against damage, and facilitate recovery. To define the global cellular adaptation response to heat stress, we performed a...
ORGANISM(S): Saccharomyces cerevisiae 
2010-04-23 | E-GEOD-17514 | biostudies-arrayexpress
UnknownPrevalence of allergic sensitization to conifer pollen in a high cypress exposure area.
Not available
S-EPMC5244279 | biostudies-literature
UnknownPhosphate control in reducing FGF23 levels in hemodialysis patients.
Not available
S-EPMC6080760 | biostudies-literature
UnknownThe mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors.
Not available
S-EPMC11470253 | biostudies-literature
UnknownInhibition of ALK3-mediated signalling pathway protects against acetaminophen-induced liver injury.
Not available
S-EPMC10902147 | biostudies-literature
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