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ProteomicsNUDCD3 deficiency disrupts V(D)J recombination to cause SCID/Omenn syndrome
Inborn errors of T cell development present a pediatric emergency in which timely curative therapy is informed by molecular diagnosis. In 9 affected patients across 3 consanguineous kindreds, we detected homozygosity for a single deleterious missense variant in the gene NudC domain containing 3 (NUD...
ORGANISM(S): Homo sapiens (Human) 
2024-09-27 | PXD035840 | Pride
Pulldown Nudcd3 Proteomics Omenn syndrome 
ProteomicsAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar ratAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar rats
Aging induces oxidative stress and proteome remodeling in the nucleus from liver in Wistar rats
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD027773 | Pride
Oxidative stress nuclear liver wistar rat lc-ms/ms 
UnknownEssential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.
Not available
S-EPMC6542366 | biostudies-literature
ProteomicsIdentification of spidroin proteins in the silk glands of Nephila clavipes spiders
Glands were frozen at -80 ºC immediately after being retrieved and stored under this condition until initiating the proteomics analysis protocol. Glands were washed with cold PBS and immersed in 120 l of homogenization buffer (50 mM Tris-HCl, pH 6.8, 10 mM DTT, 4% (w/v) SDS). Glands were boiled for ...
ORGANISM(S): Trichonephila clavipes 
2022-12-07 | PXD023141 | Pride
Spider silk  proteomics  liquid chromatography-tandem mass spectrometry  silk gut 
TranscriptomicsDiscovering novel bile protection systems in Bifidobacterium breve UCC2003 through functional genomics
Tolerance of gut commensals to bile salt exposure is an important feature for their survival in and colonization of the intestinal environment. A transcriptomic approach was employed to study the response of Bifidobacterium breve UCC2003 to bile, allowing the identification of a number of bile-induc...
ORGANISM(S): Bifidobacterium breve UCC2003 
2011-12-16 | E-GEOD-31032 | biostudies-arrayexpress
TranscriptomicsBile-inducible membrane protein mediates the bile resistance phenotype of Bifidobacterium breve UCC2003
Bbr_0838 from Bifidobacterium breve UCC2003 encodes a 683 residue membrane protein, that contains a permease domain displaying similarity to transporters belonging to the major facilitator superfamily, as well as a CBS (cystathionine beta synthase) domain. The high level of similarity to bile-efflux...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-02-20 | E-GEOD-31224 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver endothelial cells in cirrhotic rats
The study was performed in liver-endothelial cells (LECs) isolated from 6 adult male Wistar rats, undergoing a cirrhosis induction protocol as described previously by our group, and LECs isolated from 6 control Wistar rats, according to the criteria of the Investigation and Ethics Committee of the H...
ORGANISM(S): Rattus norvegicus 
2007-09-05 | E-GEOD-1843 | biostudies-arrayexpress
UnknownExcess degassing drives long-term volcanic unrest at Nevado del Ruiz.
Not available
S-EPMC10786892 | biostudies-literature
UnknownGeodetic monitoring of the recent activity and the dome forming eruption at Nevado del Ruiz (Colombia), 2010-2023.
Not available
S-EPMC11399247 | biostudies-literature
ProteomicsData deposition for publication entitled 'Proteomic analysis revealed that the oomyceticide phosphite exhibits multi-modal action in an oomycete pathosystem'
Mass spectrometry data for publication 'Proteomic analysis revealed that the oomyceticide phosphite exhibits multi-modal action in an oomycete pathosystem. Christina E. Andronis, Silke Jacques, Francisco J. Lopez-Ruiz, Richard Lipscombe and Kar-Chun Tan.'
ORGANISM(S): Lupinus Angustifolius (ncbitaxon:3871) 
2024-02-21 | MSV000094150 | MassIVE
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