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Rhinovirus causes the common cold and drives exacerbation in asthma and COPD, leading to substantial morbidity and healthcare cost. The single positive strand RNA genome of this non-enveloped virus is translated into a single polyprotein that is processed by virus 3C protease to form three structura...
ORGANISM(S): Homo sapiens (Human) 
2018-05-09 | PXD005798 | Pride
Rhinovirus (RV) is the most prevalent human respiratory virus. Each year, RV infects billions of people and is responsible for at least half of all common colds, the most common illness of humans. RV infection also affects the morbidity of a range of respiratory illnesses, such as bronchiolitis, pne...
ORGANISM(S): Homo sapiens 
In asthma there are exaggerated rather than impaired innate and adaptive interferon responses in vivo after RV16 infection, which strongly correlate with inflammation and loss of asthma control.
ORGANISM(S): Homo sapiens 
2020-01-06 | GSE106388 | GEO
This study was performed to test the hypothesis that cigarette smoke extract would alter the responses of primary cultures of human bronchial epithelial cells to infection with purified human rhinovirus 16. The data show marked alterations in rhinovirus-induced expression profiles of a number of gen...
ORGANISM(S): Homo sapiens 
Enhanced interferon response genes in bronchial epithelial cells after in vivo rhinovirus challenge of asthma patients
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