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Human transmission of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative pathogen of the coronavirus disease 2019 (COVID-19) pandemic, is exerting a massive health and socioeconomic burden. The virus infects pneumocytes, also known as alveolar epithelial type 2 (AT2) cells, ...
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2020-11-20 | PXD020183 | Pride
In Drosophila, Polycomb Response Elements (PREs) are identified as genomic sequences allowing the maintenance of transcriptional repression in the absence of the initiating signal. Although PREs in Drosophila are well characterized, the existence of mammalian PRE-like elements remains debated. Accu...
ORGANISM(S): Homo sapiens 
Protein-protein-interaction networks (PPINs) organize fundamental biological processes, but how oncogenic mutations impact these interactions and their functions at a network-level scale is poorly understood. Here, we analyze how a common oncogenic KRAS mutation (KRASG13D) affects PPIN structure and...
ORGANISM(S): Homo sapiens (Human) 
2019-12-04 | PXD016431 | Pride
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016461 | Pride
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016462 | Pride
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016463 | Pride
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