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UnknownMulti-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC4872014 | biostudies-literature
TranscriptomicsDeep sequencing data for PAM-SCANR tested CRISPR-Cas systems
In this work, we analyzed recognized PAM sequences from four CRISPR-Cas systems: E. coli I-E, B. halodurans I-C, S. thermophilus CR1 II-A, and F. novicida V. Cells containing functional PAMs were sorted using FACS and subsequently sequenced. Ranking of recognized PAMs from a positive screen
ORGANISM(S): Francisella tularensis subsp. novicida 
2016-02-17 | E-GEOD-75718 | biostudies-arrayexpress
UnknownDense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network
Not available
S-JCBD-201405099 | bioimages
TranscriptomicsTranscription profiling of human pilocytic astrocytoma to develop molecular signatures
Pilocytic astrocytomas (PAs) are the most common glioma in children. While many PAs; are slow growing or clinically indolent, others exhibit more aggressive features with tumor; recurrence and death. In order to identify genetic signatures that might predict PA clinical; behavior, we performed gene ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5675 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse neocortical and cerebellar astrocytes
Affymetrix Mouse Genome 430 2.0 GeneChip microarrays were used to analyze murine neocortical and cerbellar astrocytes generated from postnatal (PN) day 1 wild-type (ICR) pups. Experiment Overall Design: Three samples each of murine neocortical and cerebellar astrocytes were analyzed.
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5582 | biostudies-arrayexpress
ProteomicsOrbitrap mass spectrometry and high-field asymmetric waveform ion mobility spectrometry (FAIMS) enable the indepth analysis of human serum proteoforms
In this study, we describe a straightforward protocol for intact proteoform sample preparation based on depletion of albumin and immunoglobulins followed by simplified fractionation of remaining serum proteins via polyacrylamide gel electrophoresis. After molecular weight-based fractionation, we sup...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-02 | MSV000092574 | MassIVE
ProteomicsTargeted Quantification of Proteoforms in Human Samples by Proteoform Reaction Monitoring
Here, we describe an approach based on the principle of PRM for the measurement of intact proteoforms by targeted top-down proteomics termed Proteoform Reaction Monitoring (PfRM). We explore the ability of our method to circumvent traditional limitations of top-down proteomics such as sensitivity an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-21 | MSV000091774 | MassIVE
MetabolomicsDivergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies. The complex metabolic relationships that exist between members of the intestinal m...
2017-03-03 | MTBLS422 | MetaboLights
ProteomicsHuman hypertrophic cardiomyopathy cardiac tissue phosphoproteomics
This study used TMT-pro method to look for phosphoproteomic differences in heart tissue of patients with hypertrophic cardiomyopathy and controls
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-28 | MSV000091822 | MassIVE
ProteomicsHuman Cardiac Proteome of Hypertrophic Cardiomyopathy
This study utilized TMT to characterize the cardiac proteomic differences between patients with hypertrophic cardiomyopathy and controls.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-28 | MSV000091821 | MassIVE
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