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MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
ProteomicsA systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S)
We longitudinally profiled plasma proteomes in 54 adults vaccinated with the BNT162b2 (Pfizer-BioNTech) or ChAdOx1-S (Oxford-AstraZeneca) vaccines. Blood was collected pre-vaccination (V0) and 1-7 days after the 1st doses (BNT162b2 or mRNA-1273, V1) to assess innate and early adaptive responses. We ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-01 | PXD036608 | Pride
Sars-cov-2 Proteomics Plasma Vaccination Covid-19 vaccine 
TranscriptomicsTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
To gain insight into the host cell types, cellular and molecular pathways possibly involved in the differential permissiveness to pulmonary replication of M. tuberculosis, we carried out transcript profiling studies on M. tuberculosis-infected lungs from congenic and parental strains. We were partic...
ORGANISM(S): Mus musculus 
2009-02-20 | E-MEXP-1942 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lungs of C57BL6 mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
B6 mice have been infected via the aerosol route with a low-dose (100 CFUs)of Mycobacterium tuberculosis for 30 days and 70 days.

Uninfected mice have been used as experimental controls.
ORGANISM(S): Mus musculus 
2008-12-17 | E-MEXP-1899 | biostudies-arrayexpress
UnknownAcute urinary tract infection elicits bladder afferent hypersensitivity.
Not available
S-EPMC11788684 | biostudies-literature
UnknownPost-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function.
Not available
S-EPMC11602718 | biostudies-literature
Proteomics: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016512 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of full proteome profiling of SILAC labeled HCT 116 and HKE 3 cells
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD016549 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 Proteomic profiling 
ProteomicsExtensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016505 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
ProteomicsData Set3: Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
ORGANISM(S): Homo sapiens (Human) 
2019-12-02 | PXD016462 | Pride
Egfr pathway Ap-ms Interactomic Silac Proteins network Hke-3 Hct-116 
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