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ProteomicsGeneration and utilization of a monoclonal antibody against hepatitis B virus core protein for a comprehensive interactome analysis
Hepatitis B virus (HBV) core antigen (HBc) is a structural protein that forms the viral nucleocapsid and is involved in various steps of the viral replication cycle, but its role in the pathogenesis of HBV infection is still elusive. In this study, we generated a mouse monoclonal antibody against HB...
ORGANISM(S): Homo Sapiens (human) 
2023-02-21 | PXD036961 | JPOST Repository
ProteomicsPIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation
Proteomic analysis revealed potential phospho-acceptor sites within Vpx by PIM3. HEK293 cells were transfected with plasmid vector encoding Vpx together with either empty vector or PIM3. Immunoprecipitated Vpx was subjected to liquid chromatography tandem-mass spectrometry.
ORGANISM(S): Homo Sapiens (human) 
2019-03-20 | PXD013154 | JPOST Repository
ProteomicsIntegrated Tandem Affinity Protein Purification Using the Polyhistidine plus Extra 4 Amino Acids (HiP4) Tag System
Interactome analysis of HBx using a novel tag system (HiP4-tag system).
ORGANISM(S): Homo Sapiens (human) 
2023-02-28 | PXD036256 | JPOST Repository
ProteomicsIntegrated Tandem Affinity Protein Purification Using the Polyhistidine plus Extra 4 Amino Acids (HiP4) Tag System２
Interactome analysis of TARDBP (TDP-43) using a novel tag system (HiP4-tag system).
ORGANISM(S): Homo Sapiens (human) 
2023-02-28 | PXD038445 | JPOST Repository
ProteomicsDevelopment of parallel reaction monitoring mass spectrometry assay for the detection of human norovirus major capsid protein
Human Norwalk virus (HuNoVs), the most common etiological agents of acute gastroenteritis, are genetically diverse RNA viruses that frequently cause mass food poisoning internationally. In this study, we developed a parallel reaction monitoring (PRM) assay to simultaneously detect and identify repre...
ORGANISM(S): Homo Sapiens (human) Norwalk Virus 
2023-02-21 | PXD033981 | JPOST Repository
UnknownStreptococcus pneumoniae highjacks host autophagy by deploying CbpC as a decoy for Atg14 depletion
Not available
S-SCDT-EMBOR-2019-49232V1 | biostudies-other
ProteomicsDevelopment of a contacting transwell co-culture system for the in vitro culture of primary central nervous system lymphomas
Quantitative phosphoproteomic analysis of HKBML cells co-cultured with Pericytes
ORGANISM(S): Homo Sapiens (human) 
2023-11-24 | PXD043128 | JPOST Repository
ProteomicsIdentification of gravity-responsive serum proteins in spaceflight mice using a quantitative proteomic approach with data-independent acquisition mass spectrometry
Physical inactivity associated with gravity unloading, such as microgravity during spaceflight and hindlimb unloading (HU), can cause various physiological changes. In this study, we attempted to identify serum proteins whose levels fluctuated in response to gravity unloading. First, we quantitative...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-16 | PXD041894 | JPOST Repository
ProteomicsIdentification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach
The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global health concerns. Since the etiopathogenesis of this illness is not fully characterized, the prognostic factors enabling treatment decisions have not been well documented. Accurately predicting the progression of th...
ORGANISM(S): Homo Sapiens (human) 
2021-11-02 | PXD021702 | JPOST Repository
ProteomicsIdentification of gravity-responsive proteins in the femur of spaceflight mice using a quantitative proteomic approach
This project is “Medical proteome analysis of osteoporosis- and bone mass-related proteins using the Kibo Japanese Experiment Module of International Space Station (ISS)”. Utilizing proteomic technologies, this research aims to identify proteins involved in space flight-induced osteopenia as well as...
ORGANISM(S): Mus Musculus (mouse) 
2023-08-01 | PXD041738 | JPOST Repository
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