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Introduction

Hyperhomocysteinemia (HHCys) is an independent risk factor for various diseases such as cardiovascular diseases, Alzheimer's, and cancers. Folate deficiency is one of the significant reasons for HHCys. However, it is not known whether folate deficiency with HHCys is associated w...
2022-02-07 | MTBLS2150 | MetaboLights
Whole lung RNA-seq of 8 mice with experimental Schistosoma-induced pulmonary hypertension, compared to 8 control mice. All mice on a C57Bl6/J background. 3 schisto-PH and 3 control mice (#s 1-3 in each group) were also processed by Affy microarray and separately submitted. 3 of the mice in each grou...
ORGANISM(S): Mus musculus 
Changes in gene expression contribute to the long-lasting regulation of the brain's reward circuitry seen in drug addiction, however, the specific genes regulated and the transcriptional mechanisms underlying such regulation remain poorly understood. Here, we used chromatin immunoprecipitation coupl...
ORGANISM(S): Mus musculus 
This study elucidates the whole proteome changes in the MDR isolates of K. penumoniae, A. baumannii, E. coli, and P. aeruginiosa in the presence of Ampicillin, Kanamycin, and Nalidixic acid. Label-free SWATH-MS is used for protein quantitation of antibiotics treated and untreated samples.
ORGANISM(S): Klebsiella pneumoniae Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 Klebsiella pneumoniae ATCC BAA-2146 Bacteria 
2023-07-26 | PXD039154 | Pride
quantitative identification of Hsc70 clients using co-IP fallowed by nano-LC-MS/MS in autophagy altered K-ras mutant MEF cells.
ORGANISM(S): Mus Musculus (mouse) 
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a cohort of 42 subjects with different levels of glucose tolerance (...
2020-01-06 | MTBLS1051 | MetaboLights
Precisely targeting a biomolecule within living systems could create unique opportunities at the biology-medicine interface. Such methods have been non-trivial due to the complex selectivity attributes. Here, we introduce an electronically tunable chemical technology that targets N-terminal glycine,...
ORGANISM(S): Bacteria Staphylococcus aureus 
2026-10-05 | PXD082695 | Pride
DNMTs catalyze the methylation of cytosine with SAM. DNA methylation affects key cellular processes by regulating gene expression, thus serving a variety of physiological and pathophysiological roles. However, the chemical mechanisms of DNA methylation by which its enzymatic activity is regulated ha...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD039437 | Pride
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