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Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...
2021-08-20 | MTBLS608 | MetaboLights
Chromosomal and segmental aneuploidies are usually lethal or common features of cancer cells and variety of disease, but little is known about how copy number relates to gene expression. Drosophila males have a single X chromosome and two sets of autosomes, but X chromosome and autosome transcripts ...
ORGANISM(S): Drosophila melanogaster 
Total RNA-seq analysis of Ago1 or Iru-depleted Drosophila S2 cells
Small RNA-seq analysis of Ago1 or Iru-depleted Drosophila S2 cells
siRNA sequencing S2 cells
An Affimetrix GeneChip Drosophila genome 2.0 array was used to study the effect of protocatechuic aldehyde on gene expression. The addition of 0.1 mM protocatechuic aldehyde to Drosophila S2 cells significantly affected the expression of 52 genes, with 29 being up-regulated and 23 being down-regulat...
ORGANISM(S): Drosophila melanogaster 
Exosomes were isolated from S2 cells and subjected to MS. Total protein content of exsomes were compared to total proteins from S2 cells to determine which proteins were enriched and abundant in exosomes.
ORGANISM(S): Drosophila melanogaster Drosophila melanogaster (Fruit fly) 
2018-01-18 | PXD008136 | Pride
RNA-Seq on libraries made from External RNA Controls Consortium (ERCC) external RNA controls, and a mixture of mRNA from Drosophila melanogaster S2 cell and ERCC mRNAs. We evaluated performance of RNA-Seq on known synthetic PolyA+ mRNAs from the External RNA Controls Consortium (ERCC) alone and in ...
ORGANISM(S): synthetic construct 
Drosophila melanogaster strain:S2 cells Targeted Locus (Loci)
Drosophila melanogaster strain:S2 cells Transcriptome or Gene expression
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