Sadelain Michel M

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Proteomics (2)
Unknown (1)

Organisms

Alphavirus (2)
Betaherpesvirinae (2)
Brassica oleracea var. oleracea (2)
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Coxsackievirus (2)
Cytomegalovirus (2)
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EFO:0001352 (2)
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Human betaherpesvirus 5 (2)
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Nostoc sp. PCC 7120 = FACHB-418 (2)
Oropouche virus (2)
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Viruses (2)
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Repository

pride (2)

Tissue

Blood cell (1)
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T cell (1)

Disease

Acute leukemia (2)

Technology Type

Mass Spectrometry (2)
Shotgun proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (1)

Publication Date

2019 (1)
2017 (1)

Release Date

2013 (1)

Lab affiliation

Center for Cell Engineering, Memorial Sloan Kettering Cancer Center (1)
Director, Center for Cell Engineering, Sloan Kettering Institute (1)

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Transfer of antigen target into CAR T cells via trogocytosis

To characterize transfer of molecules from target cells into CAR T cells via trogocytosis we cultured NALM-6 leukemia cell line expressing a CD19-mCherry fusion protein with CAR T cells. NALM6-CD19-mCherry were loaded with heavy amino acid and cocultured with CAR T cells for 1 hour. CAR T cells wer...

ORGANISM(S): Homo sapiens (Human)

2019-03-29 | PXD012833 | Pride

An Informatic Approach to Chimeric Antigen Receptor Discovery Integrates Proteomics and Transcriptomics to Identify Novel Combinatorial Pairs

Chimeric antigen receptor (CAR) therapy targeting CD19 yielded remarkable outcomes in patients with acute lymphoblastic leukemia. To identify potential CAR targets in acute myeloid leukemia (AML), we probed the AML surfaceome for over-expressed molecules with potentially tolerable systemic expressio...

ORGANISM(S): Homo sapiens (Human)

2017-10-24 | PXD007552 | Pride

Tf Thpi Monomac Kasumi Human aml cell lines lc-msms Molm13 09aml

Clinical impact of immune microenvironment in stage I lung adenocarcinoma: tumor interleukin-12 receptor β2 (IL-12Rβ2), IL-7R, and stromal FoxP3/CD3 ratio are independent predictors of recurrence.

Not available

S-EPMC3731922 | biostudies-literature

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