Sort   by:  
 Page size 
UnknownIdentification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study.

Background

The clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine whether clinical phenotypes of patients with COVID-19 can be derived from clinical data, to assess the reproducibility of these phenotypes and correlation with prognosis,...
S-EPMC7906623 | biostudies-literature
UnknownStructure, Process, and Mortality Associated with Acute Coronary Syndrome Management in Guatemala's National Healthcare System: The ACS-GT Registry.

Background

Acute coronary syndromes (ACS) include ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (UA). The leading cause of mortality in Guatemala is acute myocardial infarction (AMI) and there is no establishe...
S-EPMC9717345 | biostudies-literature
UnknownDiscovering HIV related information by means of association rules and machine learning.
Acquired immunodeficiency syndrome (AIDS) is still one of the main health problems worldwide. It is therefore essential to keep making progress in improving the prognosis and quality of life of affected patients. One way to advance along this pathway is to uncover connections between other disorders...
S-EPMC9616424 | biostudies-literature
UnknownShaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity.
The frequency of mitochondrial DNA haplogroups (mtDNA-HG) in humans is known to be shaped by migration and repopulation. Mounting evidence indicates that mtDNA-HG are not phenotypically neutral, and selection may contribute to its distribution. Haplogroup H, the most abundant in Europe, improved sur...
S-EPMC11718132 | biostudies-literature
UnknownProcalcitonin and C-reactive protein to rule out early bacterial coinfection in COVID-19 critically ill patients.

Purpose

Although the prevalence of community-acquired respiratory bacterial coinfection upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been reported to be < 5%, almost three-quarters of patients received antibiotics. We aim to investigate whether procalciton...
S-EPMC10425511 | biostudies-literature
UnknownConsiderations and consequences of allowing DNA sequence data as types of fungal taxa.
Nomenclatural type definitions are one of the most important concepts in biological nomenclature. Being physical objects that can be re-studied by other researchers, types permanently link taxonomy (an artificial agreement to classify biological diversity) with nomenclature (an artificial agreement ...
S-EPMC6048565 | biostudies-literature
UnknownImmunosuppressed patients with COVID-19 pneumonia in ICU: clinical characteristics and factors influencing outcomes.

Introduction

COVID-19 severely impacted global health, especially older adults and those with comorbidities. Immunosuppressed patients are at high risk for severe outcomes, yet studies yield conflicting mortality rates for this group. This study examines the clinical characteristics and outc...
S-EPMC12645730 | biostudies-literature
UnknownDouble reflex testing improves the efficacy and cost effectiveness of hepatitis delta diagnosis in southern Spain.
This study aims to evaluate the prevalence of undiagnosed hepatitis delta in southern Spain (Andalusia) and assess the effectiveness and cost-efficiency of implementing reflex testing for hepatitis D detection in HBsAg-positive patients. A multicenter ambispective study was conducted in 17 Andalusia...
S-EPMC12048655 | biostudies-literature
UnknownThe evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients.

Background

Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at...
S-EPMC8436582 | biostudies-literature
UnknownNovel genes and sex differences in COVID-19 severity.
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In sex-disaggregated genome-wide association studies for COVID-1...
S-EPMC9652109 | biostudies-literature
Sort   by:  
 Page size