Sort   by:  
 Page size 
ProteomicsThe olfactory secretome varies according to season in female sheep and goat
Background: Small ungulates (sheep and goat) display a seasonal breeding, characterised by successive periods of sexual activity (SA) and sexual rest (SR). In sexual activity period the ovarian cycle of females is active and ready for reproduction (oestrus) whereas in sexual rest no ovulation and re...
ORGANISM(S): Ovis aries Capra hircus (Goat) 
2019-11-06 | PXD014833 | Pride
Olfactory secretome Seasonality Ungulates Reproduction 
ProteomicsIdentification of potential chemical signals in the European water vole Arvicola terrestris
The water vole Arvicola terrestris (= Arvicola amphibious L.) is endemic in Europe where its outbreak generates severe economic losses for farmers. Our project aimed at deciphering the modalities of chemical communication in this species, to develop new sustainable methods for populations control. T...
ORGANISM(S): Arvicola 
2019-12-11 | PXD013803 | Pride
Lateral scent glands Urinary volatiles Arvicolin Gc-ms Water vole De novo sequencing Odorant binding proteins Arvicola terrestris 
ProteomicsEssential role of GEXP15, a specific Protein Phosphatase type 1 partner in Plasmodium berghei in asexual erythrocytic proliferation and transmission
The essential and distinct functions of Protein Phosphatase type 1 (PP1) catalytic subunit in eukaryotes are exclusively achieved through its interaction with a myriad of regulatory partners. In this work, we report the molecular and functional characterization of Gametocyte EXported Protein 15 (GEX...
ORGANISM(S): Plasmodium berghei ANKA 
2019-07-16 | PXD013874 | Pride
Pp1 Phosphatase Ip-ms Plasmodium 
ProteomicsStreamlining of defenses against copper makes host-restricted pathogen reliant on custom-made operon
Copper is both essential and toxic to living beings, which therefore tightly control its intracellular concentration. At the host-pathogen interface, copper is used by phagocytic cells to kill invading microorganisms. We investigated copper homeostasis in the whooping cough agent Bordetella pertussi...
ORGANISM(S): Bordetella bronchiseptica 
2021-09-09 | PXD020900 | Pride
Host-restricted pathogen Oxidative stress Bordetella pertussis Evolution Metallochaperone Copper homeostasis Phagocytosis 
ProteomicsHepatitis C virus alters the morphology and function of peroxisomes.
Despite the introduction of effective treatments for hepatitis C in clinics, issues remain regarding the liver diseases induced by chronic hepatitis C virus (HCV) infection. HCV is known to disturb the metabolism of infected cells, especially lipid metabolism and redox balance, but the mechanisms le...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD044994 | Pride
Crispr-cas9 Peroxisome Apex2 Jfh1 Dbn3a Proximity biotinylation Ros Hepatitis c virus Hcv genotype 
ProteomicsMHC II immunopeptidome during Plasmodium berghei blood stage infection
In malaria, T cells play a dual role by both restricting parasite growth and mediating immunopathology such as the deadly neuroinflammation called cerebral malaria. During experimental cerebral malaria (ECM), IFN produced by CD4 T cells promotes CD8 T cell sequestration in brain capillaries, result...
ORGANISM(S): Mus musculus (Mouse) Plasmodium berghei ANKA 
2017-09-20 | PXD007628 | Pride
Lc-msms Malaria Mouse Mhc ii Plasmodium berghei 
Sort   by:  
 Page size