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ProteomicsSopB and SifA modify the proteome of the Salmonella-containing vacuole in the social amoeba Dictyostelium discoideum
Salmonella enterica serovar Typhimurium is a rod-shaped Gram-negative bacterium. It is a leading cause of gastroenteritis and public health problem. In the environment, it interacts with protozoa, particular amoeba, however the interactions between Salmonella and these eukaryotic microbes have not b...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) Dictyostelium discoideum (Slime mold) 
2020-09-23 | PXD014955 | Pride
Salmonella Dictyostelium Salmonella-containing vacuole 
TranscriptomicsTranscription profiling of Salmonella enterica Typhimurium during infection of human epithelial cells
Epithelial cells are the first cell type Salmonella Typhimurium will encounter when infecting a host. Using DNA array techology we identified the Salmonella enterica Typhimurium genes regulated inside human epithelial cells and their variation through time.
ORGANISM(S): Salmonella typhimurium 
2009-04-08 | E-MEXP-1368 | biostudies-arrayexpress
ProteomicsSalmonella mediated intracellular niche control by SCV size regulation
Salmonella is a human and animal pathogen causing gastro-enteric diseases worldwide. The key feature of Salmonella infection is its entry into intestinal epithelial cells within a Salmonella-Containing Vacuole (SCV). This original compartment is distinct from empty macropinosomes formed around the...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2020-01-09 | PXD012825 | Pride
Membrane trafficking Membrane rupture Magnetic extraction Tubule formation Macropinosome Membrane fusion Salmonella containing vacuole Snare Salmonella enterica serovar typhimurium Svat 
GenomicsA CRISPR knockout screen revealed modulators of Chlamydia trachomatis parasitophorous vacuole stability
Chlamydia trachomatis is a prevalent bacterial cause of urogenital and ocular infections. The pathogen uses the effector CpoS to suppress a host defense response that aborts intracellular bacterial growth by inducing host cell death. We conducted a CRISPR knockout screen to identify host genes contr...
ORGANISM(S): Homo sapiens 
2025-07-10 | E-MTAB-15337 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of S. Typhimurium cells residing in the food vacuole (phagosome) of the bacteria grazing ciliate Tetrahymena
The gene expression of Salmonella enterica Typhimurium MB282 residing in the food vacuole (phagosome) of Tetrahymena was analyzed by microarray. A minimum of three biological replicates were used. Each biological rep was comprised of at least two technical replicate arrays. MB282 incubated in H2O an...
ORGANISM(S): Salmonella enterica 
2010-04-13 | E-GEOD-21308 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of 14 regulators required for Salmonella virulene
To cause a systemic infection, Salmonella must respond to many environmental cues during mouse infection and express specific subsets of genes in a temporal and spatial manner, but the regulatory pathways are poorly established. To unravel how micro-environmental signals are processed and integrated...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S 
2012-05-30 | E-GEOD-38378 | biostudies-arrayexpress
TranscriptomicsIntracellular proliferation and virulence gene expression of Salmonella are influenced by pre-invasion growth conditions
Salmonella invasion of non-phagocytic cells is a dynamic process that requires the translocation of effector proteins into host cells by a type III secretion system (T3SS1) encoded on Salmonella pathogenicity island 1 (SPI1). The signals involved in T3SS1 induction in vivo are not known, but SPI1-in...
ORGANISM(S): Salmonella typhimurium SL1344 
2010-04-19 | E-GEOD-13343 | biostudies-arrayexpress
ModelsScheidel2016 - In Silico Knockout Studies of Xenophagy Capturing of Salmonella
Xenophagy, also known as antibacterial autophagy, is a process of capturing and eliminating cytosolic pathogens, like Salmonella. Salmonella is the best-studied model organism for xenophagy. We present a Petri net model of Salmonella xenophagy in epithelial cells. The model is based on functional i...
2020-04-09 | MODEL1904150001 | BioModels
UnknownDynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche.
Not available
S-EPMC6931108 | biostudies-literature
UnknownSopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole.
Not available
S-EPMC6682159 | biostudies-literature
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