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ProteomicsDeep quantitative proteomics underlies extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells
Endometriosis is a prevalent health condition in women of reproductive age characterized by ectopic growth of endometrial tissue in the extrauterine environment. Thorough understanding of the molecular mechanisms underlying the disease are still lacking and incomplete. We dissect eutopic and ectopic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-22 | MSV000080276 | MassIVE
ProteomicsBovine sperm plasma membrane proteomics through biotinylation and subcellular enrichment
Mammalian fertilization requires a complex interplay between a sperm cell and an oocyte. A significant proportion of these functions are mediated through the proteomic composition of the sperm surface. These proteomic constituents can present as biomarkers to control and regulate breeding of agricul...
ORGANISM(S): Bos taurus (Bovine) 
2015-03-19 | PXD001096 | Pride
Plasma membrane proteome Reproductive biology Biotinylation Bos taurus Sperm cell 
ProteomicsDeep quantitative proteomics underlies extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells
Endometriosis is a prevalent health condition in women of reproductive age characterized by ectopic growth of endometrial tissue in the extrauterine environment. Thorough understanding of the molecular mechanisms underlying the disease are still lacking and incomplete. We dissect eutopic and ectopic...
ORGANISM(S): Homo sapiens (Human) 
2015-12-21 | PXD002845 | Pride
Stromal cell Proteomics Endometrium Silac Endometriosis Warburg effect 
ProteomicsHuman primary endometrial stromal cells (proliferative vs secretory) LC-MSMS - proteins and phosphosites
Our study explores the phosphorylation pathways in decidualization, focussing on four major targets of interest – cAMP-dependent protein kinase, Rho-dependent protein kinase (ROCK), protein kinase B, and casein kinase 2. Our goal was to pinpoint the changes in protein kinase activity profile during ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-21 | PXD026243 | Pride
Human Lc-msms Endometrium Endometrial stromal cell Decidualization 
TranscriptomicsInteractome of Human Embryo Implantation: Identification of Gene Expression Pathways, Regulation, and Integrated Regulatory Networks.
Possible interactions between endometrium and implanting embryo in humans
ORGANISM(S): Homo sapiens 
2011-12-16 | E-MEXP-3111 | biostudies-arrayexpress
TranscriptomicsEndometrial methylome of patients without endometriosis
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73949 | biostudies-arrayexpress
TranscriptomicsEndometrial methylome of patients with endometriosis
Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73948 | biostudies-arrayexpress
UnknownGut microbiome in endometriosis: a cohort study on 1000 individuals.
Not available
S-EPMC11256574 | biostudies-literature
OtherBovine sperm plasma membrane proteomics through biotinylation and subcellular enrichment.
Data from ProteomeXchange, PXD ID: PXD001096. File: 130508_01_Orbi1_SK_SER_G150_T158_BOSS_2xenrich_repl1_try.mzml. Published as part of Proteomics. 2015 Jan 20 . From the Abstract: {{i}} A significant proportion of mammalian fertilization is mediated through the proteomic composition of the sperm s...
ORGANISM(S): Cow 
GPM32320014064 | GPMDB
Resource Reanalysis 
TranscriptomicsEpigenetic regulation of receptive human endometrium through microRNAs
MicroRNAs (miRNAs) act as important epigenetic post-transcriptional regulators of gene expression. We aimed to gain more understanding to the complex gene expression regulation of endometrial receptivity by analysing miRNA signature of fertile human endometrium. We used Agilent miRNA arrays to defi...
ORGANISM(S): Homo sapiens 
2012-06-22 | E-GEOD-34435 | biostudies-arrayexpress
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