Poly(ADP-ribosylation)(PARylation)is apost-translational modification mediated by asubset of ADP-ribosyl transferases (ARTs). Although PARylation-inhibition based therapies areconsidered as an avenue to combat debilitating diseases such as cancerand myopathies, the roleof thismodificationinphysiolog...
ORGANISM(S): Mus musculus (Mouse)
