Sort   by:  
 Page size 
ProteomicsSORLA upregulation suppresses global pathological effects in aged tauopathy mouse brain
A role for the type I transmembrane trafficking receptor SORLA in reducing Aβ levels has been well-established, however, virtually nothing is known with respect to whether and how SORLA can potentially affect tau pathology. Here, we show that transgenic SORLA upregulation (SORLA TG) can reverse path...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-24 | PXD056276 | Pride
Tauopathy Alzheimer’s disease Tau Plexin Semaphorin Sorla Tau pathology 
UnknownDetecting nitrous oxide reductase (NosZ) genes in soil metagenomes: method development and implications for the nitrogen cycle.
Not available
S-EPMC4049103 | biostudies-literature
UnknownAutocrine function of aldehyde dehydrogenase 1 as a determinant of diet- and sex-specific differences in visceral adiposity.
Not available
S-EPMC3526050 | biostudies-literature
UnknownEx vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.
Not available
S-EPMC4383769 | biostudies-literature
UnknownOrenia metallireducens sp. nov. Strain Z6, a Novel Metal-Reducing Member of the Phylum Firmicutes from the Deep Subsurface.
Not available
S-EPMC5066361 | biostudies-literature
UnknownIncreased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.
Not available
S-EPMC5138112 | biostudies-literature
UnknownA circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment.
Not available
S-EPMC4752664 | biostudies-literature
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
UnknownNeuronal ceroid lipofuscinosis type CLN2: a new rationale for the construction of phenotypic subgroups based on a survey of 25 cases in South America.
Not available
S-EPMC3855401 | biostudies-literature
UnknownAssociation of myeloperoxidase with ovarian cancer.
Not available
S-EPMC4039294 | biostudies-literature
Sort   by:  
 Page size