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MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
TranscriptomicsTranscription profiling of rat liver response to CYP450 inducers for array validation
The main objectives were to validate the DNA array technology and establish the degree of correlation between any compound-induced effects on gene expression with those at the level of histological examination.
ORGANISM(S): Rattus norvegicus 
2004-01-22 | E-MEXP-52 | biostudies-arrayexpress
ProteomicsHuman DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
To date few DDK substrates other than the MCM helicase have been identified, and none are implicated in fork protection or restart. Here we searched for such factors, using SILAC and quantitative mass spectrometry to identify the DDK phosphoproteome during fork stalling.
ORGANISM(S): Homo sapiens (Human) 
2021-06-29 | PXD014399 | Pride
Lc-ms/ms Chemical genetics Cdc7 Ddk Stalled forks Analogue-sesitive Phosphoproteomics Replication 
UnknownSimvastatin in Critically Ill Patients with Covid-19.
Not available
S-EPMC10755839 | biostudies-literature
MetabolomicsCirculating cell populations as response predictors and targets to improve immunotherapy in metastatic lung cancer

The effectiveness of immunotherapy varies among patients with advanced non-small cell lung cancer (NSCLC). Here we investigated the baseline immune status in stage IV NSCLC patients treated with anti-PD-1 plus chemotherapy to understand the immune mechanisms and unveil systemic markers associated...

2025-10-16 | MTBLS13150 | MetaboLights
UnknownEffect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC10326520 | biostudies-literature
UnknownEffect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC8941448 | biostudies-literature
UnknownLong-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Not available
S-EPMC9857594 | biostudies-literature
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
UnknownRisk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
Not available
S-EPMC6306365 | biostudies-literature
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