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ProteomicsObscurin and Obsl1 functions for “Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.”
“Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.”
ORGANISM(S): Mus musculus (Mouse) 
2019-05-20 | PXD013008 | Pride
Obscurin Obsl1 Sarcoplasmic reticulum organization Muscle metabolism Sarcolemmal integrity 
UnknownReduced Sarcolemmal Membrane Repair Exacerbates Striated Muscle Pathology in a Mouse Model of Duchenne Muscular Dystrophy.
Not available
S-EPMC9100510 | biostudies-literature
UnknownMurine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.
Not available
S-EPMC6509138 | biostudies-literature
UnknownTreatment with Recombinant Human MG53 Protein Increases Membrane Integrity in a Mouse Model of Limb Girdle Muscular Dystrophy 2B.
Not available
S-EPMC5628796 | biostudies-literature
UnknownProteomic analysis of the dysferlin protein complex unveils its importance for sarcolemmal maintenance and integrity.
Not available
S-EPMC2974636 | biostudies-literature
UnknownCell membrane integrity in myotonic dystrophy type 1: implications for therapy.
Not available
S-EPMC4370802 | biostudies-literature
UnknownLoss of Lipin1 Contributes to Multiple Pathological Processes in the Development of Heart Failure.
Not available
S-EPMC12826883 | biostudies-literature
UnknownUncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization.
Not available
S-EPMC3920738 | biostudies-literature
TranscriptomicsExcess muscle plasma membrane leak disrupts extracellular matrix content and shifts macrophage-mediated muscle repair [scRNA-Seq]
Plasma membrane repair is critical for tissue integrity, especially for elongated contractile muscle cells. Genetically-mediated defects in plasma membrane resealing produce persistent leak, leading to a disordered extracellular matrix. Loss of the membrane repair protein dysferlin slows sarcolemmal...
ORGANISM(S): Mus musculus 
2026-06-15 | GSE328601 | GEO
TranscriptomicsExcess muscle plasma membrane leak disrupts extracellular matrix content and shifts macrophage-mediated muscle repair
Plasma membrane repair is critical for tissue integrity, especially for elongated contractile muscle cells. Genetically-mediated defects in plasma membrane resealing produce persistent leak, leading to a disordered extracellular matrix. Loss of the membrane repair protein dysferlin slows sarcolemmal...
ORGANISM(S): Mus musculus 
2026-06-15 | GSE328583 | GEO
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