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TranscriptomicsLost miRNA surveillance of NOTCH, IGFR pathway-road to sarcomagenesis [Exiqon]
The goal of this study was comparative analysis of differentially expressed miRNA and their targets in human chondrosarcoma JJ012 and chondrocytes C28 cell line (control) to elucidate the major signal transduction pathways deregulation in sarcomagenesis. Total RNA extraction was followed by the anal...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-48396 | biostudies-arrayexpress
TranscriptomicsLost miRNA surveillance of NOTCH, IGFR pathway-road to sarcomagenesis [Illumina]
The goal of this study was comparative analysis of differentially expressed miRNA and their targets in human chondrosarcoma JJ012 and chondrocytes C28 cell line(control) to elucidate the major signal transduction pathways deregulation in sarcomagenesis. Total RNA extraction was followed by the analy...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-48418 | biostudies-arrayexpress
ProteomicsProteomics Analysis of Human Mesenchymal Stromal/Stem Cell Sarcomagenesis Model Identifies ALDH1A3 and CD99 as Potential Targets in the Transformation Process
Mesenchymal stromal/stem cells (MSC) may represent the cell-of-origin for sarcoma development. A collection of human MSCs sequentially mutated with an increasing number of oncogenic hits served to recreate a step-wise process of sarcomagenesis. To identify potential protein targets of interest in th...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD069892 | Pride
Msc-sarcoma model Sarcomagenesis Cd99 Proteomics (lc-ms/ms) Aldh1a3 
TranscriptomicsExpression following beta-catenin stabilization in synovial sarcomagenesis
Synovial sarcoma is a deadly soft-tissue malignancy with a predilection for adolescents and young adults. Mice recapitulate synovial sarcomagenesis from expression of SS18-SSX2 in certain cells. Concomitant expression of a stabilized form of beta-catenin enhances synovial sarcomagenesis and expands ...
ORGANISM(S): Mus musculus 
2015-11-04 | GSE47388 | GEO
UnknownThe Influential Role of BCL2 Family Members in Synovial Sarcomagenesis.
Not available
S-EPMC5816685 | biostudies-literature
TranscriptomicsExpression following beta-catenin stabilization in synovial sarcomagenesis
Synovial sarcoma is a deadly soft-tissue malignancy with a predilection for adolescents and young adults. Mice recapitulate synovial sarcomagenesis from expression of SS18-SSX2 in certain cells. Concomitant expression of a stabilized form of beta-catenin enhances synovial sarcomagenesis and expands ...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-47388 | biostudies-arrayexpress
UnknownYAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Not available
S-EPMC6314302 | biostudies-literature
TranscriptomicsLost miRNA surveillance of NOTCH, IGFR pathway-road to sarcomagenesis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-48420 | biostudies-arrayexpress
UnknownAkt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor.
Not available
S-EPMC387332 | biostudies-literature
UnknownParacrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells.
Not available
S-EPMC5749548 | biostudies-literature
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