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It has remained unknown how cells reduce cystine taken up from the extracellular space, which is a required step for further utilization of cysteine in key processes such as protein or glutathione synthesis. Here we show that the thioredoxin-related protein of 14 kDa (TRP14, encoded by TXNDC17) is t...
ORGANISM(S): Homo sapiens (Human) 
2024-05-10 | PXD050368 | Pride
Identification of cysteinylated proteins in parental HEK cells and TRP14 knockdown HEK cells.
ORGANISM(S): Homo sapiens (Human) 
2024-05-10 | PXD050210 | Pride
Cancer Stem Cells derived from from human non-small cells lung cancer (NSCLC) H460 cells were differentiated by culturing them in the presence of Foetal Bovine Serum under adherent conditions. Changes in gene expression profiles were determined at 3, 9 and 24 hours of differentiation Expression prof...
ORGANISM(S): Homo sapiens 
Transcription profile of cancer stem cells isolated from human non-small cells lung cancer (NSCLC) H460 cells. The profile of H460 cells that were made resistant to cisplatin after a single treatment with the drug was also determined. Both profiles were finally compared. Each microarray contained on...
ORGANISM(S): Homo sapiens 
Ewing’s Sarcoma (ES) is characterized by specific chromosomal translocations, the most common being t(11;22)(q24;q12). Additionally, other types of genetic abnormalities may occur and be relevant to explain the variable tumoural biology and clinical outcome. We have carried out a high-resolution a...
ORGANISM(S): Homo sapiens 
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