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MetabolomicsGlycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway configurations ...
2022-01-11 | MTBLS3887 | MetaboLights
ProteomicsExtensive regulation of enzyme activity by phosphorylation in Escherichia coli
This project contains intact protein MS and PRM data for several central metabolic enzymes in E.coli. The enzymes are both wild-type and mutant for several
ORGANISM(S): Escherichia coli 
2021-08-20 | PXD027243 | Pride
E coli Top down proteomics Intact protein 
MetabolomicsGNPS - Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities
Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-03-13 | MSV000091478 | GNPS
MetabolomicsRedox proteomics reveal a role for peroxiredoxinylation in stress protection.

The redox state of proteins is essential for their function and guarantees cell fitness. Peroxiredoxins protect cells against oxidative stress, maintain redox homeostasis, act as chaperones, and transmit hydrogen peroxide signals to redox regulators. Despite the profound structural and functional...

2025-07-17 | MTBLS11979 | MetaboLights
TranscriptomicsExpression data from wild-type FY4 and GCR2 deletion strain
Expression data from wild-type FY4 and GCR2 deletion strain. Impact of the transcription factor Gcr2p on mRNA expression was investigated in the corresponding deletion strain in exponentially growing glucose minimal medium batch cultures. Both streins were grown on glucose minimal medium and harvest...
ORGANISM(S): Saccharomyces cerevisiae 
2010-03-06 | E-GEOD-19569 | biostudies-arrayexpress
ModelsKuepfer2005 - Genome-scale metabolic network of Saccharomyces cerevisiae (iLL672)
Kuepfer2005 - Genome-scale metabolic network of Saccharomyces cerevisiae (iLL672) This model is described in the article: Metabolic functions of duplicate genes in Saccharomyces cerevisiae. Kuepfer L, Sauer U, Blank LM. Genome Res. 2005 Oct; 15(10): 1421-1430 Abstract: ...
2015-07-30 | MODEL1507180066 | BioModels
ProteomicsGlobal coordination of metabolic pathways in Escherichia coli by active and passive regulation
In this study, we identify the regulatory mechanisms that coordinate catabolism and anabolism in the bacterium Escherichia coli. Integrating protein, metabolite, and metabolic flux changes in genetically implemented gradual catabolic or anabolic limitations, we show that a combination of global and ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2021-03-03 | MSV000086992 | MassIVE
TranscriptomicsNon-growing Rhodopseudomonas palustris increases the hydrogen gas yield from acetate by shifting from the glyoxylate shunt to the tricarboxylic acid cycle
Transcriptome analysis was performed in order to better understand the metabolic activity of non-growing cells of Rhodopseudomonas palustris for improve biofuel production. Gene expression profilings of cells from various time points during non-growing phase were compared using RNA-seq.
ORGANISM(S): Rhodopseudomonas palustris CGA009 
2014-02-04 | E-GEOD-51825 | biostudies-arrayexpress
TranscriptomicsThe IHF regulon of exponentially growing Pseudomonas putida cells
Integration host factor (IHF) sites are largely absent from intergenic regions of ORFs encoding central metabolic functions in Pseudomonas putida mt-2. To gain an insight into this unequal distribution of otherwise abundant IHF-binding sequences, the transcriptome of IHF-plus and IHF-minus cells gro...
ORGANISM(S): Pseudomonas putida 
2012-07-24 | E-GEOD-23499 | biostudies-arrayexpress
TranscriptomicsBacillus subtilis 168 cells: wild-type vs. ccpN (non polar)
Global transcriptional profiling of Bacillus subtilis cells comparing wild-type to a ccpN (yqzB) non polar mutant. Abstract of associated publication (article accepted): The transcriptional regulator CcpN of Bacillus subtilis has been recently characterized as a repressor of two gluconeogenic genes...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2008-06-26 | E-GEOD-11873 | biostudies-arrayexpress
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