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UnknownDynamics of saxitoxin binding to saxiphilin c-lobe reveals conformational change.
Not available
S-EPMC2262801 | biostudies-literature
UnknownStructure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins.
Not available
S-EPMC6584486 | biostudies-literature
UnknownDefinition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Not available
S-EPMC9636910 | biostudies-literature
ProteomicsAlkaloids modify the poison frog proteome
Poison frogs sequester chemical defenses from their diet of leaf litter arthropods for defense against predation. Little is known about the physiological adaptations that confer this unusual bioaccumulation ability. We conducted an alkaloid-feeding experiment with the Diablito poison frog (Oophaga s...
ORGANISM(S): Oophaga sylvatica 
2021-01-25 | PXD021216 | Pride
Complement system Toxin Skin Gut Liver Saxiphilin Cytochrome p450s Poison dart frog 
UnknownSaxiphilin functions as a 'toxin sponge' protein that counteracts the effects of saxitoxin poisoning.
Not available
S-EPMC12667915 | biostudies-literature
UnknownNovel modulator of Na(V)1.1 and Na(V)1.2 Na channels in rat neuronal cells.
Not available
S-EPMC2894714 | biostudies-literature
UnknownRapid toxin sequestration modifies poison frog physiology.
Not available
S-EPMC7888741 | biostudies-literature
UnknownBinding and sequestration of poison frog alkaloids by a plasma globulin.
Not available
S-EPMC10783871 | biostudies-literature
UnknownEvidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins.
Not available
S-EPMC8348241 | biostudies-literature
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