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In this study the targetome of the endonuclease Cas9 and a CRISPR-associated small RNA (scaRNA/NMnc0040) was determined in Neisseria meninigitidis serogroup C strain 8013 by quantitative proteomics.
ORGANISM(S): Neisseria meningitidis serogroup C (strain 8013) 
2026-08-07 | PXD037567 | Pride
Enhancers predominantly control transcription initiation [scaRNA-seq]
LSM7 Coordinates scaRNA-Mediated snRNA Modification to Ensure Spliceosome Fidelity and Spermatogonial Stem Cell Differentiation
LSM7 Coordinates scaRNA-Mediated snRNA Modification to Ensure Spliceosome Fidelity and Spermatogonial Stem Cell Differentiation [RIP-Seq]
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs are non-coding RNAs involved in the maturation of other RNA molecules. Alterations of sno/scaRNA expression may play a role in cancerogenesis. This study elucidates the patterns of sno/scaRNA expression in highly purified cells from 2...
ORGANISM(S): Homo sapiens 
Spermatogenesis requires precise spatial and temporal regulation of RNA splicing, orchestrated by both the major (U1, U2, and U4/U6/U5) and minor (U11, U12, and U4atac/U6atac/U5) spliceosomal small nuclear ribonucleoproteins (snRNPs), yet their function during germ cell development remain poorly def...
ORGANISM(S): Mus musculus 
2026-05-20 | GSE304556 | GEO
Spermatogenesis requires precise spatial and temporal regulation of RNA splicing, orchestrated by both the major (U1, U2, and U4/U6/U5) and minor (U11, U12, and U4atac/U6atac/U5) spliceosomal small nuclear ribonucleoproteins (snRNPs), yet their function during germ cell development remain poorly def...
ORGANISM(S): Mus musculus 
2026-05-20 | GSE304555 | GEO
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs (scaRNAs) are non-coding RNAs involved in the maturation of other RNA molecules and generally located in the introns of host genes. It is now emerging that altered sno/scaRNAs expression may play a pathological role in cancer. This st...
ORGANISM(S): Homo sapiens 
Small Cajal body-specific RNAs (scaRNA) are conserved small noncoding RNAs that guide post-transcriptional modification of spliceosomal RNA (snRNA), a key step for accurate spliceosome biogenesis and function. Despite scaRNA expression being altered in cancer, how this impacts pre-mRNA splicing rema...
ORGANISM(S): Homo sapiens 
2021-07-15 | GSE156376 | GEO
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