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TranscriptomicsA family of secreted pathogenesis-related proteins in Candida albicans
Analyzing culture supernatants of yeast and hyphal cells of Candida albicans by mass spectrometry, we found two close homologues of pathogenesis-related (PR-) 1 proteins, Rbe1p and Rbt4p, in the secretome of this human pathogen. By sequence homology, we assigned three yet not characterized open read...
ORGANISM(S): Candida albicans 
2013-03-25 | E-GEOD-28212 | biostudies-arrayexpress
TranscriptomicsTiling array hybridizations of genomic DNA from Staphylococcus aureus HG001.
This analysis is part of the study Whole-transcriptome analysis of Staphylococcus aureus under laboratory and infection-mimicking conditions (Mäder, Nicolas et al., to be submitted) where the S. aureus HG001 transcriptome was analyzed under more than 40 different bilogical conditions. Genomic DNA w...
ORGANISM(S): Staphylococcus aureus 
2016-03-08 | E-GEOD-70042 | biostudies-arrayexpress
TranscriptomicsElucidating the Linezolid response of Staphylococcus aureus USA300 by a holistic study
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus 
2016-02-22 | E-GEOD-65209 | biostudies-arrayexpress
UnknownAllelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires.
Not available
S-EPMC10440473 | biostudies-literature
TranscriptomicsThe condition-dependent transcriptome of Bacillus subtilis 168
Recent studies revealed the unsuspected complexity of the bacterial transcriptome but its systematic analysis across many diverse conditions remains a challenge. Here we report the condition-dependent transcriptome of the prototype strain B. subtilis 168 across 104 conditions reflecting the bacteriu...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2012-03-07 | E-GEOD-27219 | biostudies-arrayexpress
TranscriptomicsRNA processing in Bacillus subtilis: Identification of targets of the essential RNase Y
RNA processing and degradation is initiated by endonucleolytic cleavage of the target RNAs. In many bacteria, this activity is performed by RNase E which is not present in Bacillus subtilis and other Gram-positive bacteria. Recently, the essential endoribonuclease RNase Y has been discovered in B. s...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2011-08-31 | E-GEOD-30430 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of glucose starved Bacillus subtilis cells
In this study, temporal changes in the proteome, transcriptome and extracellular metabolome of B. subtilis caused by glucose starvation were monitored. For proteomic profiling, a combination of in vivo metabolic labeling and shot gun mass spectrometric analysis was carried out for five different pro...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2010-12-01 | E-GEOD-24058 | biostudies-arrayexpress
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