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ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of DLD-1 and MDA-MB-231 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset also includes DLD-1 cells treated with FT671 (USP7 inhibitor) at 10 µM for 30 min and 6 h. Sample IDs: #1-5 Control 3...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD075275 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of DLD-1 and MDA-MB-231 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset also includes DLD-1 cells treated with FT671 (USP7 inhibitor) at 10 µM for 30 min and 6 h.Sample IDs:#1-5 Control 30 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073869 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of UO-31 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). Sample IDs:#1-5 Control 30 min UO-31#6-10 WEHI-092 30 min UO-31#11-15 Control 360 min UO-31#16-20 WEHI-092 360 min UO-31#21-25 Control 24 h UO-31...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073754 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of SK-MEL-2 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). Sample IDs:#31-35 Control 30 min SK-MEL-2#36-40 WEHI-092 30 min SK-MEL-2#41-45 Control 360 min SK-MEL-2#46-50 WEHI-092 360 min SK-MEL-2#51-55 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073775 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Treatment of cancer cells MDA-MB-231 and MiaPaca2 with WEHI-092 (10 uM, 24 h) or FT709 (10 uM, 24 h). Sample key of raw file in ZIP folder: #1-6 MDA-MB-231 DMSO (untreated); #13-18 MDA-MB-231 FT709; #19-24 MDA-MB-231 WEHI-092; #25-30 MiaPaca2 DMSO (untreated); #37-42 MiaPaca2 FT709; #43-48 MiaPaca2 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD074729 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Mass spectrometry-based 3X-FLAG-Ub-VS deubiquitinase (DUB) competition assay with cell extracts (DUB IP-MS) profiling MCF-7 cells with regard to specificity of WEHI-092, a selective inhibitor for USP9X. Sample key: #1-5 Untreated; #6-10 Ub-VS pre-treatment; #11-15 WEHI-092 treated (50 µM, 60 min).
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD074545 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
HDX-MS experiment using selective USP9X inhibitors WEHI-092, FT709 with recombinant catalytic domain USP9X.
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD062754 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Global proteomics experiment using USP9X siRNA (and control) MDA-MB-231 cells with (10 µM, 24 h) and without USP9X inhibitor treatment using WEHI-092 and untreated (DMSO) control (P5448, see sample key). Global proteomics experiment profiling cancer cell lines treated with USP9X inhibitor WEHI-092 (...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD062674 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Global proteomics dataset for K-GG ubiquitin profiling of DLD-1 and MDA-MB-231 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset also includes DLD-1 cells treated with FT671 (USP7 inhibitor) at 10 µM for 30 min and 6...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD074673 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of SK-MEL-2 and UO-31 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset is the matched global quantitative proteomics data.Sample IDs:#1-5 Control 30 min UO-31#6-10 WEHI-092 30 min UO-31#11-1...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073798 | Pride
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