Sort   by:  
 Page size 
ModelsSchilling2009 - ERK distributive
Schilling2009 - ERK distributive This model has been exported from PottersWheel on 2009-04-20 18:57:44.  The PottersWheel Model Definition file can be obtained from the curation tab. This model is described in the article: Theoretical and experimental analysis links ...
2024-09-02 | BIOMD0000000270 | BioModels
ProteomicsIdentification of novel natural substrates of fibroblast activation protein by differential degradomics and proteomics
Fibroblast Activation Protein (FAP) is a cell-surface transmembrane-anchored anchored dimeric protease. This unique constitutively active serine protease has both dipeptidyl aminopeptidase and endopeptidase activities, and can hydrolyse post-proline bonds. FAP expression is very low in adult organs,...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-19 | PXD004754 | Pride
Protease 
ProteomicsIdentification of novel natural substrates of fibroblast activation protein by differential degradomics and proteomics (TAILS dataset)
Fibroblast Activation Protein (FAP) is a cell-surface transmembrane-anchored anchored dimeric protease. This unique constitutively active serine protease has both dipeptidyl aminopeptidase and endopeptidase activities, and can hydrolyse post-proline bonds. FAP expression is very low in adult organs,...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-19 | PXD004757 | Pride
Seprase Proteolysis 
ProteomicsThe Skin Barrier Defects Caused by Keratinocyte-Specific Deletion of ADAM17 or EGFR are Based on Highly Similar Proteome and Degradome Alterations
ADAM17 and EGFR are essential key players for epidermal integrity. Keratinocyte-specific deletion of ADAM17 in mice results in pronounced alterations in terminal differentiation of keratinocytes leading to severe epidermal barrier defects with enhanced transepidermal water loss. Thereby, mice defici...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-20 | PXD002597 | Pride
Proteomics Skin Degradomics 
ProteomicsSRRM4/nSR100 directs neuronal-specific microexon splicing of TAF1 mRNA involved in X-linked Dystonia-Parkinsonism
X-linked dystonia-parkinsonism is a neurodegenerative disease, which is caused by a SVA retrotransposon insertion within TAF1, gene encoding an integral component of the basal transcription factor TFIID. The SVA insertion has been shown to induce defects both in biosynthesis and in alternative splic...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD009905 | Pride
Co-immunoprecipitation Epidgenetics 
UnknownDouble deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
Not available
S-EPMC11113308 | biostudies-literature
ProteomicsProteome profiles of primary pancreatic ductal adenocarcinomas undergoing adjuvant chemoradiation link ALDH1A1 to early local recurrence and chemoradiation resistance
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis with very frequent post-surgical local recurrence. The combination of adjuvant chemotherapy with radiotherapy is under consideration to achieve a prolonged disease-free survival (DFS). To date, few studies have determined protein profiles ...
ORGANISM(S): Homo sapiens (Human) 
2018-09-11 | PXD009254 | Pride
Maoa Chemoradiation Aldh1a1 
UnknownIdentification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin.
Not available
S-EPMC6117259 | biostudies-literature
ModelsBecker2010_EpoR_CoreModel
This is the core model described in the article: Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor Verena Becker, Marcel Schilling, Julie Bachmann, Ute Baumann, Andreas Raue, Thomas Maiwald, Jens Timmer and Ursula K...
2024-09-02 | BIOMD0000000271 | BioModels
ModelsBecker2010_EpoR_AuxiliaryModel
This is the auxiliary model described in the article: Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor Verena Becker, Marcel Schilling, Julie Bachmann, Ute Baumann, Andreas Raue, Thomas Maiwald, Jens Timmer and Urs...
2024-09-02 | BIOMD0000000272 | BioModels
Sort   by:  
 Page size