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TranscriptomicsProtein kinase A regulated genes of Aspergillus fumigatus -FEBIT transcriptome analysis
Aspergillus fumigatus is a ubiquitous mould but also an opportunistic human pathogen causing life-threatening infections in immunocompromised patients. Survival of the fungus in different habitats depends on effective mechanisms of signal perception and transduction such as the cAMP dependent protei...
ORGANISM(S): Aspergillus fumigatus 
2014-11-30 | E-MTAB-2783 | biostudies-arrayexpress
ProteomicsA quantitative proteomic analysis of in vitro assembled chromatin
The structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store epigenetic information. It is defined by the histone molecules that constitute the nucleosome, the positioning of the nucleosomes along the DNA and the non-histone prote...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-01-27 | PXD002537 | Pride
Acetylation  affinity proteomics  chromatin function or biology  label-free quantification   macromolecular assemblages 
ProteomicsA time-resolved atlas of histone modifications during mitotic entry
Mitotic chromosome formation is essential for faithful chromosome segregation in metazoans. While condensin complexes are critical for the formation of rod-shaped mitotic chromosomes, additional mechanisms—particularly those involving phosphorylation and deacetylation of specific histone residues—ha...
ORGANISM(S): Gallus gallus (Chicken) 
2026-05-13 | PXD066101 | Pride
Chicken Ptms Mitosis Histones Lcms 
MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
UnknownIn-tube dynamic extraction for analysis of volatile organic compounds in honey samples.
Not available
S-EPMC9130071 | biostudies-literature
ProteomicsIntricate structure of the interphase chromocenter revealed by the analysis of a factor involved in species formation
In higher eukaryotes centromeres often coalesce into a large intranuclear domain called the chromocenter. Chromocenters are important for the organization of pericentric heterochromatin and a disturbance of their formation results in an upregulation of repetitive elements and causes defects in chrom...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-03-23 | PXD012551 | Pride
Chromatin proteomics Drosophila Chromocenter Centromeres 
ProteomicsDREX proteome analysis for spectral library
In order to prepare a spectral library for data-indepentend acquisition mass spectrometry studies, we try to cover as many proteins from Drosophila melanogaster embryonic protein extracts.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-02-25 | PXD005100 | Pride
Drosophila embryo proteome Fragmentation pattern Spectral library 
ProteomicsFishing for SAM/SAH-binding proteins
The aim of the project was to identify S-adenodsyl methionine-binding proteins expressed in D. melanogaster S2 cells. For this puprose a capture compund reagent carrying a SAH-affinity group, a biotin group for enrichment and a cross-linking moiety consisting of either benzophenone or a nitrobenzen...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-02-25 | PXD006245 | Pride
Capture compound S-adenosyl-methionine Lysine methylation Methyltransferase 
ProteomicsATM INDUCES MACROD2 NUCLEAR EXPORT UPON DNA DAMAGE
ADP-ribosylation is a dynamic post-translation modification that regulates the early phase of various DNA repair pathways by recruiting repair factors to chromatin. ADP-ribosylation levels are defined by the activities of transferases and hydrolases. Little is known about regulation of these enzymes...
ORGANISM(S): Homo sapiens (Human) 
2016-10-12 | PXD003712 | Pride
Atm phosphorylation Dna damage Nuclear export Regulation of adp-ribosylation 
ProteomicsSensing and signalling of DNA breaks in extracts of preblastoderm Drosophila embryos
Preblastoderm Drosophila embryos replicate their genomes at maximal speed. The assembly of chromatin on the newly synthesized chromosomes relies entirely on high concentrations of maternal nucleosome assembly and remodelling factors. Extracts from preblastoderm embryos can be turned into a system fo...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-10-14 | PXD013130 | Pride
Dna repair Dna damage response D.melanogaster 
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