This a model from the article:
Network-level analysis of light adaptation in rod cells under normal and altered conditions.
Dell'Orco D, Schmidt H, Mariani S, Fanelli F
Mol Biosyst2009 Oct; 5(10):1232-46
19756313,
Abstract:
Photoreceptor...
Smoothened (SMO)-inhibitors recently entered clinical trials for sonic-hedgehog driven medulloblastoma (SHH-MB). Clinical response appears highly variable. To understand the mechanism(s) of primary resistance and to identify pathways co-operating with aberrant SHH-signaling, we sequenced a large coh...
1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435)
2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)
Focal segmental glomerulosclerosis (FSGS) represents a pattern of injuries seen in histopathology rather than a distinct disease. Presently, FSGS is categorized into primary, genetic, and secondary types, although these subcategories probably encompass significantly diverse pathogeneses. Here, we pe...
Smoothened (SMO)-inhibitors recently entered clinical trials for sonic-hedgehog driven medulloblastoma (SHH-MB). Clinical response appears highly variable. To understand the mechanism(s) of primary resistance and to identify pathways co-operating with aberrant SHH-signaling, we sequenced a large coh...
Inflammatory bowel disease (IBD), comprising CrohnM-BM-4s disease and Ulcerative colitis, is characterized by chronic relapsing inflammation of the gut. It has been shown that increased proteasomal activity is associated with the expression of immunoproteasomes, which enhances NF-kB activation and t...
Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by early metastasis into lung and bone. Genetically, ES are defined by balanced chromosomal EWS/ETS translocations, which give rise to chimeric proteins (EWS-ETS) that generate an oncogenic trans...
Tuberculosis (TB) is a contagious disease that is a primary cause of mortality and illness in around a quater of the world' population particular in low income nations. The disease most commonly affects lung, but pathogens can also be found in other parts of the body. Mycobacterium tuberculosis (Mtb...
ORGANISM(S): Homo sapiens (Human) Mycobacterium tuberculosis
Article title: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells. Glucocorticoids (GCs) cause apoptosis and cell cycle arrest in lymphoid cells and constitute a central component in ...
