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Wilms tumour (nephroblastoma) is the most common paediatric renal tumour, affecting 1 in 10,000 children. Despite the excellent survival of patients treated with a combination of surgery, chemotherapy and radiotherapy, approximately 15% will relapse and die of this disease. We have identified CACNA1...
ORGANISM(S): Homo sapiens 
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
Phytophthora infestans is a major pathogen of potato and tomato, a key determinant to the successful outcome of disease laying with the effector proteins secreted by the pathogen during infection; these collectively act to facilitate evasion of plant immunity, physical breaching of the plant tissue,...
ORGANISM(S): Phytophthora infestans T30-4 
2026-02-13 | PXD072961 | Pride
Clavibacter michiganensis subsp. michiganensis is an important Gram-positive phytopathogenic bacteria that causes bacterial wilt and canker in tomato. The genome of the type strain, NCPPB382, has been sequenced and annotated, however comparative genomics suggests that certain regions are under- or m...
ORGANISM(S): Clavibacter michiganensis subsp. michiganensis NCPPB 382 
2019-01-31 | PXD006787 | Pride
Timecourse of 9-(S)-HODE treatment of Drosophila S2 cells. 9-(S)-HODE is an oxygenated metabolite of the abundant, 18 carbon, omega-6 PUFA linoleic acid. To discriminate how omega-6 PUFAs affect meta-inflammation S2 cells were with 10uM for 12 and 24hrs and microarrays performed to identify downstre...
ORGANISM(S): Drosophila melanogaster 
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