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MetabolomicsHorizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights
MetabolomicsSystematic identification of metabolites controlling gene expression in E. coli
Metabolism controls gene expression through allosteric interactions between metabolites and transcription factors. These interactions are usually measured with in vitro assays, but there are no methods to identify them at a genome-scale in vivo. Here we show that dynamic transcriptome and metabolome...
2019-08-23 | MTBLS1044 | MetaboLights
ProteomicsMS imaging of tryptic peptides in mouse brain measured at 50 µm pixel size
A coronal mouse brain section that was measured at 50µm pixel size revealed detailed histological structures such as the ependyma (consisting of one to two cell layers, which was confirmed by HE staining).
ORGANISM(S): Mus musculus (Mouse) 
2018-08-08 | PXD003172 | Pride
Proteins Tryptic peptides Mouse brain Trypsin 
ProteomicsBiomineralization of Mantis Shrimp Dactyl Club during Development: Apatite Formation and Brominated Organic Components
The stomatopod Odontodactylus scyllarus uses weaponized clubs like appendages to attack its prey. These clubs are made of apatite, chitin, amorphous calcium carbonate, and amorphous calcium phosphate ordered in a highly hierarchical structure with multiple regions and layers. We follow the developme...
ORGANISM(S): Cellular Organisms 
2023-10-05 | PXD037177 | JPOST Repository
ProteomicsMass spectrometry imaging of phospholipids in mouse urinary bladder (imzML dataset)
The spatial distribution of phospholipids in a tissue section of mouse urinary bladder was analyzed by MALDI MS imaging at 10 micrometer pixel size with high mass resolution (using an LTQ Orbitrap mass spectrometer).
ORGANISM(S): Mus musculus (Mouse) 
2014-11-19 | PXD001283 | Pride
Tissue imaging Imzml Phospholipids Mass spectrometry imaging Mouse urinary bladder 
TranscriptomicsExpression data from primary Glioblastoma in adults
Gene expression profiling revealed over-representation of a distinct (proneural-like) expression signature in long-term survivors that was linked to IDH1/2 mutation. However, among the IDH1/2-wildtype patients, tumors from long-term survivors did not show distinct gene expression profiles and includ...
ORGANISM(S): Homo sapiens 
2014-03-27 | E-GEOD-53733 | biostudies-arrayexpress
Genomics20190219_EGA_MelanomaOnTreatment - samples
Illumina platform sequencing data for matched tumour-normal DNA samples from 77 melanoma patients participating in a study investigating response to immunotherapy. Selected cases also have RNA sequencing of the tumour.
EGAD00001004869 | EGA
Genomics20210303_EGA_Melanoma - samples
RNAseq of 55 melanoma tumors that were used as a validation dataset in Garg et al Nat Commun,  2021 Feb 18;12(1):1137. doi: 10.1038/s41467-021-21207-2.
EGAD00001007055 | EGA
UnknownComparison of cable bacteria genera reveals details of their conduction machinery
Not available
S-SCDT-10_1038-S44319-025-00387-8 | biostudies-other
GenomicsAnalysis of translatome, truncating mutations, lncRNA, circRNA and microproteins of 80 human DCM cases and controls
The regulation of gene expression in healthy and diseased human tissues is incompletely understood and has primarily been studied on the transcriptional level. Here, we quantify the impact of translation on gene expression and annotate novel translational events in 80 human hearts. These include 65 ...
EGAS00001003263 | EGA
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