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GenomicsRelapsed and Primary Neuroblastoma DAC
Data Access Committee EGAC00001000373
EGAC00001000373 | EGA
ProteomicsCell-autonomous hepatocyte-specific GP130 signalling alone is sufficient to trigger robust innate immune response in mice
Members of the IL-6 cytokine family contribute to inflammatory and regenerative processes. Engagement of the signalling receptor subunit gp130 is common to almost all members of the family. In the liver, all major cell types respond to IL-6, making it difficult to delineate cell type-specific effect...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-20 | PXD020744 | Pride
Innate immunity Acute-phase response Il-6 Gp130 
GenomicsGenomes of Relapsing Neuroblastoma
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs, but the molecular mechanisms behind this process are poorly defined. We here used whole-exome sequencing, mRNA expression, array CGH and DNA methylation analysis to holistically chara...
EGAS00001001387 | EGA
Genomicsena-DATASET-UKEssen-09-09-2015-10:54:33:815-144 - samples
In this dataset, 16 trios- primary tumor, relapse and corresponding normals- for patients with neuroblastoma are provided. For one patient, more than one relapse was available for the analyses.
EGAD00001001607 | EGA
Genomics1fcf2848-b51f-450f-a20d-02c6d8156eb7 - samples
Dataset consists of fastq files of Ribo-seq, polyA-RNA and total RNA sequencing of 80 samples (65 DCM cases and 15 controls)
EGAD00001004394 | EGA
GenomicsAnalysis of translatome, truncating mutations, lncRNA, circRNA and microproteins of 80 human DCM cases and controls
The regulation of gene expression in healthy and diseased human tissues is incompletely understood and has primarily been studied on the transcriptional level. Here, we quantify the impact of translation on gene expression and annotate novel translational events in 80 human hearts. These include 65 ...
EGAS00001003263 | EGA
GenomicsDAC for Cardiac Translatomes of 80 Human Samples (65 DCM cases 15 controls)
Data Access Committee EGAC00001001040
EGAC00001001040 | EGA
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