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ProteomicsRescue of oxytocin response and social behavior in a rodent model of autism
One of the most fundamental challenges in developing treatments for autism-spectrum disorders is the heterogeneity of the condition. More than one hundred genetic mutations confer high risk for autism, with each individual mutation accounting for only a small fraction of autism cases. Subsets of ris...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-27 | PXD018808 | Pride
Autism Prm Mass spectrometry 
ProteomicsTargeted proteoform mapping uncovers specific Neurexin-3 variants required for dendritic inhibition
Diversification of cell adhesion molecules by alternative splicing is proposed to underlie molecular codes for neuronal wiring. Transcriptomic approaches mapped detailed cell type-specific mRNA splicing programs. However, it has been hard to probe synapse-specific localization and function of the re...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-11 | PXD031379 | Pride
Ap-ms Neurexin-3 Targeted ms 
UnknownLondon Dispersion Interactions Rather than Steric Hindrance Determine the Enantioselectivity of the Corey-Bakshi-Shibata Reduction.
Not available
S-EPMC7986100 | biostudies-literature
ProteomicsA ternary Neurexin-T178-PTPR complex represents a core-module of neuronal synapse organization
Complexes of synaptic adhesion molecules instruct the formation, functional specification and plasticity of neuronal synapses. Proteomic and candidate gene studies have identified an array of synaptic adhesion molecules that may cooperate or provide independent columns connecting synaptic compartmen...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2026-07-24 | PXD054017 | Pride
Mouse Synapse Neuron Brain Ap-ms. ms 
UnknownRecognition of the regulatory nascent chain TnaC by the ribosome.
Not available
S-EPMC3244694 | biostudies-literature
UnknownThe Life with Corona survey.
Not available
S-EPMC9167047 | biostudies-literature
UnknownEffectiveness and Safety of High- vs Low-Dose Swallowed Topical Steroids for Maintenance Treatment of Eosinophilic Esophagitis: A Multicenter Observational Study.
Not available
S-EPMC8108396 | biostudies-literature
UnknownNo Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis.
Not available
S-EPMC12038721 | biostudies-literature
UnknownThe whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species.
Not available
S-EPMC5034548 | biostudies-literature
UnknownImprovements in Walking Distance during Nusinersen Treatment - A Prospective 3-year SMArtCARE Registry Study.
Not available
S-EPMC9881023 | biostudies-literature
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