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TranscriptomicsHuman BRAF-V600E melanoma cell lines drug sensitive vs drug resistant
aCGH of human melanoma cell lines comparing parental (drug sensitve) vs isogenic drug resistant-derived subline Two condition experiment: two BRAF-V600E mutant cell lines (drug sensitive - parental baseline) vs two derived sublines after chronic exposure to the MEK inhibitor trametinib (drug resista...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-49430 | biostudies-arrayexpress
UnknownAutomated cassette-based production of high specific activity [203/212Pb]peptide-based theranostic radiopharmaceuticals for image-guided radionuclide therapy for cancer.
Not available
S-EPMC6295910 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownDrug repurposing screens identify chemical entities for the development of COVID-19 interventions.
Not available
S-EPMC8175350 | biostudies-literature
UnknownDosimetry of [212Pb]VMT01, a MC1R-Targeted Alpha Therapeutic Compound, and Effect of Free 208Tl on Tissue Absorbed Doses.
Not available
S-EPMC9504749 | biostudies-literature
UnknownEffect of combined tobacco use and type 2 diabetes mellitus on prevalent fibrosis in patients with MASLD.
Not available
S-EPMC10615418 | biostudies-literature
UnknownDisulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper.
Not available
S-EPMC7299833 | biostudies-literature
ProteomicsMicroenvironment Shapes Small Cell Lung Cancer Neuroendocrine States and Presents Unique Therapeutic Opportunities
Small-cell lung cancer (SCLC) is the most fatal form of lung cancer. Intra-tumoral heterogeneity, marked by neuroendocrine (NE) and non-neuroendocrine (non-NE) cell states, defines SCLC, but the drivers of SCLC plasticity are poorly understood. To map the landscape of SCLC tumor microenvironment (TM...
ORGANISM(S): Homo sapiens (Human) 
2024-05-15 | PXD052033 | Pride
Small cell lung cancer  tumor microenvironment  tumor heterogeneity  spatial transcriptomics  cancer associated fibroblasts  intercellular communication  rapid research autopsy 
UnknownSARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans.
Not available
S-EPMC8695127 | biostudies-literature
UnknownAfrican-Lineage Zika Virus Replication Dynamics and Maternal-Fetal Interface Infection in Pregnant Rhesus Macaques.
Not available
S-EPMC8312872 | biostudies-literature
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