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GenomicsEpigenomic landscapes of human inflammation associated macrophages
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-02-28 | E-GEOD-66595 | biostudies-arrayexpress
TranscriptomicsGC424 tumor cells and gastric tumors
This SuperSeries is composed of the following subset Series: GSE27710: Gene expression profiles of control GC424 tumor cell lines and after downregulation of the SV40 large T-antigen GSE27711: Gene expression profiles of spontaneous gastric tumors in the antrum of the stomach of 30,60, and 90 day ol...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-27712 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of control GC424 tumor cell lines and after downregulation of the SV40 large T-antigen
Analysis of global gene expression in a tumor cell line established from a CEA424-Tag mouse and comparison with the expressed gene profile after downregulating the expression of the large T antigen Total RNA obtained from cultured control cell lines and after siRNA mediated downregulation of the SV...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-27710 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of spontaneous gastric tumors in the antrum of the stomach of 30,60, and 90 day old CEA424-SV40 -T antigen transgenic mice.
Analysis of global gene expression in the antral portion of the stomach in control and mice with a developing tumor to get further insight into the exact tumor type and the influence of local gene expression. Total RNA obtained from tissue samples from the antrum. Follow up of gene expression over ...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-27711 | biostudies-arrayexpress
TranscriptomicsCX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-63147 | biostudies-arrayexpress
TranscriptomicsCX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (expression)
Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-63118 | biostudies-arrayexpress
TranscriptomicsCX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq)
Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Homo sapiens 
2016-06-10 | E-GEOD-63144 | biostudies-arrayexpress
TranscriptomicsTranscriptome wide analysis of untreated, classically and alternatively activated macrophages
Analysis of human M0-, M1-, and M2-like macrophages. Total RNA was isolated from untreated, classically and aternative activated human macrophages
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-35449 | biostudies-arrayexpress
TranscriptomicsTranscriptome wide analysis of classically and alternatively activated macrophages
Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived human M1- and M2-like macrophage profiling (RNA-seq) to microarray and quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods an...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-36952 | biostudies-arrayexpress
TranscriptomicsIncreased antigen cross-presentation but impaired cross-priming after activation of PPARγ
Increased antigen cross-presentation but impaired cross-priming after activation of PPARγ is mediated by up-regulation of B7H1 Dendritic cells (DCs) are able to take up exogenous antigens and present antigen-derived peptides on MHC class I molecules, a process termed cross-presentation. The mannose...
ORGANISM(S): Mus musculus 
2010-05-08 | E-GEOD-15616 | biostudies-arrayexpress
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