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TranscriptomicsExpression data from developing regulatory T cells
CD25+ regulatory T cells develop in the thymus (nTregs), but may also be generated in the periphery upon stimulation of naive CD4 T cells under appropriate conditions (iTregs). The mechanisms that regulate the generation of peripheral iTregs are largely unknown. We used microarrays to gain insights ...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-GEOD-24634 | biostudies-arrayexpress
UnknownMutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.
Not available
S-EPMC6486497 | biostudies-literature
TranscriptomicsFracture healing in osteoporotic mice
Genome-wide comparative gene expression analysis of callus tissue of osteoporotic mice (Col1a1-Krm2 and Lrp5-/-) and wild-type were performed to identify candidate genes that might be responsible for the impaired fracture healing observed in Col1a1-Krm2 and Lrp5-/- mice. To investigate bone healing ...
ORGANISM(S): Mus musculus 
2013-10-25 | E-GEOD-51686 | biostudies-arrayexpress
MetabolomicsA data set of 255000 randomly selected and manually classified extracted ion chromatograms for evaluation of peak detection methods

Nontargeted mass spectrometry (MS) has become an important method over the last years in the fields of metabolomics and environmental research. While more and more algorithms and workflows become available to process a large number of data sets nontargeted, there still exist few manually evaluate...

2020-05-26 | MTBLS1455 | MetaboLights
MetabolomicsSemi‐polar root exudates in natural grassland communities
In the rhizosphere, plants are exposed to a multitude of different biotic and abiotic factors, to which they respond by exuding a wide range of secondary root metabolites. So far, it has been unknown to which degree root exudate composition is species-specific and is affected by land use, the local ...
2018-08-15 | MTBLS671 | MetaboLights
UnknownAnalysis of the transcriptional program of developing induced regulatory T cells.
Not available
S-EPMC3036712 | biostudies-literature
TranscriptomicsGene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription
The AF4/FMR2 proteins AFF1 and AFF4 act as a scaffold to assemble the Super Elongation Complex (SEC) that strongly activates transcriptional elongation of HIV-1 and cellular genes. Although they can dimerize, it is unclear whether the dimers exist and function within a SEC in vivo. Furthermore, it i...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-69021 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine DCIS and invasive ductal breast carcinoma
Murine healthy tissue samples, DCIS and invasive mammary tumors were analyzed in order to identify marker genes which show enhanced expresssion in DCIS and invasive ductal carcinomas. Using this approach, we were able to identify a set of genes which might allow a better detection of DCIS and invasi...
ORGANISM(S): Mus musculus 
2011-04-11 | E-GEOD-21444 | biostudies-arrayexpress
UnknownIdentification of genes and pathways associated with cytotoxic T lymphocyte infiltration of serous ovarian cancer.
Not available
S-EPMC2938262 | biostudies-literature
ProteomicsUncovering metabolic regulatory mechanisms connected to rubber biosynthesis by the down-regulation of CPTL1 in Taraxacum koksaghyz
The Russian dandelion Taraxacum koksaghyz synthesizes considerable amounts of high molecular weight rubber in its roots. The cis-1,4-isoprene polymers are stored as rubber particle in the latex, the cytosol of specialized cells, called laticifers. The rubber transferase complex localizes at the part...
ORGANISM(S): Taraxacum sp. 
2022-03-02 | PXD010953 | Pride
Proteomics Rna interference Prenyltransferase Triterpenes Lipids Rubber Taraxacum koksaghyz 
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