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TranscriptomicsDual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer
Using a retrovirus-mediated cDNA expression cloning approach we identified the grainyhead-like 2 (GRHL2) transcription factor as novel protooncogene. Overexpression of GRHL2 in NIH3T3 cells induced striking morphological changes, an increase in cell proliferation, anchorage-independent growth, and t...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-43610 | biostudies-arrayexpress
UnknownInvestigator initiated trials versus industry sponsored trials - translation of randomized controlled trials into clinical practice (IMPACT).
Not available
S-EPMC8406615 | biostudies-literature
ProteomicsPharmacoproteomics of non-human primate cerebrospinal fluid after BACE inhibition
The protease BACE1 is a major drug target for Alzheimer’s disease, but chronic BACE1 inhibition is associated with non-progressive worsening that may be caused by modulation of unknown physiological BACE1 substrates. To identify in vivo-relevant BACE1 substrates we applied pharmacoproteomics to non-...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2023-02-23 | PXD035141 | Pride
Bace Beta secretase Cerebrospinal fluid Alzheimer's disease Csf 
TranscriptomicsImmune response eQTL study in primary human monocytes stimulated with multiple microbial ligands under multiple time points
Gene expression arrays and genotyping data in primary human monocytes from healthy individuals of European ancestry that have either been unstimulated (baseline), exposed to Lipopolysaccharide (90 minutes or 6 hours duration), muramyl-dipeptide (90 minutes or 6 hours duration) or transfected with 5’...
ORGANISM(S): Homo sapiens 
2017-05-16 | E-MTAB-5631 | biostudies-arrayexpress
UnknownGenome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.
Not available
S-EPMC3059436 | biostudies-literature
Genomicsena-DATASET-MPIMG-04-05-2016-11:08:19:631-106 - samples
Whole-genome sequencing on Illumina HiSeq2000/2500 of colorectal cancer metastasis sample
EGAD00001002084 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:21:37:629-120 - samples
Whole-exome sequencing on Illumina HiSeq2000/2500 of Patient-derived xenograft derived from colorectal cancer metastasis sample
EGAD00001002098 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:25:47:437-127 - samples
Whole-exome sequencing on AB 5500xl Genetic Analyzer of colorectal cancer metastasis sample
EGAD00001002105 | EGA
Genomicsena-DATASET-MPIMG-04-05-2016-11:10:37:045-110 - samples
Whole-genome sequencing on Illumina HiSeq2000/2500 of colorectal cancer primary tumor sample
EGAD00001002088 | EGA
Genomicsena-DATASET-MPIMG-15-06-2017-11:16:33:021-1359 - samples
RNAseq on Illumina HiSeq2000/2500 of Patient-derived xenograft derived from colorectal cancer metastasis sample (OT2_cohort)
EGAD00001003366 | EGA
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