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TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
TranscriptomicsAnalysis of the Pseudomonas aeruginosa regulon controlled by the sensor kinase KinB and sigma factor RpoN
Alginate overproduction by P. aeruginosa, also known as mucoidy is associated with chronic endobronchial infections in cystic fibrosis (CF). Alginate biosynthesis in this bacterium is initiated by the extracytoplasmic function sigma factor (σ22, AlgU/T). In the wild type (wt) nonmucoid strains, su...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-03-01 | E-GEOD-35248 | biostudies-arrayexpress
TranscriptomicsTranscriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease during long-term missions. Further, this research field unveils new insights into connections between low fluid-shear regions encountere...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2011-06-28 | E-GEOD-22684 | biostudies-arrayexpress
UnknownMitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans.
Not available
S-EPMC4067970 | biostudies-literature
UnknownMitochondrial genome sequence analysis: a custom bioinformatics pipeline substantially improves Affymetrix MitoChip v2.0 call rate and accuracy.
Not available
S-EPMC3234255 | biostudies-literature
TranscriptomicsSalmonella Typhimurium transcription profiles in space flight
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115, and compared to profiles from Salmonella grown under identical conditions on the ground. Keywords: stress response, transcriptional profile Triplicate experimental samples were hybridized to slides t...
ORGANISM(S): Salmonella enterica 
2007-09-13 | E-GEOD-8573 | biostudies-arrayexpress
UnknownSpace flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq.
Not available
S-EPMC2042201 | biostudies-literature
UnknownMedia ion composition controls regulatory and virulence response of Salmonella in spaceflight.
Not available
S-EPMC2592540 | biostudies-literature
UnknownWorldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study.
Not available
S-EPMC10544712 | biostudies-literature
UnknownSex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia.
Not available
S-EPMC10867777 | biostudies-literature
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