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ModelsPfeiffer2001_ATP-ProducingPathways_CooperationCompetition
This model is from the article: Cooperation and Competition in the Evolution of ATP-Producing Pathways Thomas Pfeiffer, Stefan Schuster, Sebastian Bonhoeffer Science 2001 Apr; Volume:292 (Issue:5516); Page info:504-7 11283355 ...
2024-09-02 | BIOMD0000000337 | BioModels
UnknownC/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.
Not available
S-EPMC1224679 | biostudies-literature
TranscriptomicsTranscriptome analysis in macrophages treated with type I interferon, heat-killed Listeria monocytogenes, or both.
To define the group of genes which is synergistically induced by cooperative activity of the type I interferon - activated Jak/STAT pathway and other pathways, we treated bone marrow-derived macrophages (BMDM) with heat-killed Listeria (hkL; non-STAT pathways activated), type I interferon alone (onl...
ORGANISM(S): Mus musculus 
2015-06-15 | E-MTAB-3015 | biostudies-arrayexpress
MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
TranscriptomicsArabidopsis light and temperature response
High-density kinetic analysis of the metabolomic and transcriptomic response of Arabidopsis to temperature and light
ORGANISM(S): Arabidopsis thaliana 
2011-08-09 | E-MTAB-375 | biostudies-arrayexpress
TranscriptomicsIntegrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
The saprophytic mold Aspergillus fumigatus produces small (2-3 µm) airborne spores (conidia) that can reach the lung alveoli upon inhalation. There, they encounter the surfactant-rich environment of the alveolar epithelium and initiate swelling and germination. Primary alveolar macrophages are essen...
ORGANISM(S): Homo sapiens 
2026-10-02 | E-MTAB-17130 | biostudies-arrayexpress
ProteomicsMicroenvironment Shapes Small Cell Lung Cancer Neuroendocrine States and Presents Unique Therapeutic Opportunities
Small-cell lung cancer (SCLC) is the most fatal form of lung cancer. Intra-tumoral heterogeneity, marked by neuroendocrine (NE) and non-neuroendocrine (non-NE) cell states, defines SCLC, but the drivers of SCLC plasticity are poorly understood. To map the landscape of SCLC tumor microenvironment (TM...
ORGANISM(S): Homo sapiens (Human) 
2024-05-15 | PXD052033 | Pride
Small cell lung cancer  tumor microenvironment  tumor heterogeneity  spatial transcriptomics  cancer associated fibroblasts  intercellular communication  rapid research autopsy 
ProteomicsFASN-dependent de novo lipogenesis is required for brain development
Fate and behaviour of neural progenitor cells is tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing molecular building blocks to generate cells, govern progenitor function. H...
ORGANISM(S): Homo sapiens (Human) 
2022-01-14 | PXD026110 | Pride
Fasn Human Mouse Lipogenesis Brain development Brain organoids 
TranscriptomicsEVOREPRO: Amborella
Amborella expression atlas
ORGANISM(S): Amborella trichopoda 
2021-04-14 | E-MTAB-9190 | biostudies-arrayexpress
TranscriptomicsRNA-seq transcriptome profiling of the psychrophilic diatom Fragilariopsis cylindrus under six treatments simulating conditions within sea ice
We performed RNA-sequencing experiments to examine gene expression in the genome of the cold-adapted (psychrophilic) marine diatom Fragilariopsis cylindrus to six different treatments simulating conditions found within sea ice. RNA-seq was performed on replicate samples for each experimental conditi...
ORGANISM(S): Fragilariopsis cylindrus 
2018-01-18 | E-MTAB-5153 | biostudies-arrayexpress
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