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ProteomicsSecretome profiling of human airway epithelial cultures infected with respiratory syncytial virus
The respiratory epithelium is a polarised layer at the interface between the outside environment and deeper lung structures, overlaid by the epithelial lining fluid (ELF). This provides a mechanical and immunological barrier to inhaled particulates, such as viruses. Human respiratory syncytial virus...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD004430 | Pride
Human respiratory syncytial virus Human airway epithelial model Secretome Lc-ms/ms 
UnknownMatrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI.
Not available
S-EPMC12483517 | biostudies-literature
ProteomicsThe secretome profiling of a pediatric airway epithelium infected with hRSV identified aberrant apical/basolateral trafficking and novel immune modulating (CXCL6, CXCL16, CSF3) and antiviral (CEACAM1) proteins.
The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-25 | PXD013661 | Pride
Cxcl16 Secretome directionality Respiratory syncytial virus Well-differentiated pediatric bronchial epithelial cells (wd-pbecs) Ceacam1 Quantitative proteomics Cxcl6 Csf3 
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