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In the present work neutrophil subcellular fractionation by density gradient centrifugation was conducted in order to perform a quantitative proteomic profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005559 | Pride
This study addresses the need for non-invasive methods to assess the human endometrium, which is critical for successful pregnancy and is implicated in unexplained infertility. The primary biological relevance lies in determining if extracellular vesicles in uterine fluid (UF-EVs) can serve as a pro...
ORGANISM(S): Homo sapiens 
Parkinson disease (PD) is the second most common age-related neurodegenerative disorder, which is related to neurotransmitter secretion impartment and the dysfunction of vesicle transport. Secretory granules (SGs) are a class of intracellular vesicles different from synaptic vesicles (SVs) in neuron...
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD023937 | Pride
Neurons and endocrine cells package peptides in secretory granules (large dense core vesicles; LDCVs) for storage and stimulated release. Studies of PAM, an essential secretory granule membrane enzyme, revealed a pathway that can relay information from secretory granules to the nucleus, resulting i...
ORGANISM(S): Mus musculus 
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