Sort   by:  
 Page size 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 6/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Mus musculus (Mouse) synthetic construct 
2025-02-26 | PXD036668 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 4/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-02-26 | PXD036662 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 3/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD036661 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 5/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): synthetic construct 
2025-02-26 | PXD036666 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 1/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD036658 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsEngineered Peptide Barcodes for Binding Protein Generation
Binding protein generation relies on laborious screening cascades that process candidate molecules individually. To break with this paradigm, we developed NestLink, a binder selection and identification technology able to biophysically characterize thousands of library members at once without handli...
ORGANISM(S): synthetic construct (code 12) 
2019-01-15 | PXD009301 | Pride
Peptide barcode 
ProteomicsRapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
Escherichia coli is a major cause of blood stream and urinary tract infections. Owing to the spread of antimicrobial resistance, it is often treated with an inadequate antibiotic. With the aim to accelerate the diagnostics of this key pathogen, we used the flycode technology to generate nanobodies a...
ORGANISM(S): Escherichia coli 
2025-06-11 | PXD054264 | Pride
Lc-ms/ms Nestlink E. coli 
ProteomicsTargeted proteomic analysis of single glomeruli
WE analyzed the proteome of single mouse glomeruli using DDA and PRM.
ORGANISM(S): Mus musculus (Mouse) 
2018-06-28 | PXD006903 | Pride
Kidney Wt1 Fsgs Glomeruli 
ProteomicsShotgun proteomics analysis of single human tubules
We analyzed microdissected single tubules from human with shotgun proteomics.
ORGANISM(S): Homo sapiens (Human) 
2018-06-28 | PXD006897 | Pride
Human Proximal tubule Kidney 
ProteomicsPRM assay for functional tubule proteomics
We used a targeted proteomics assay to survey proximal tubule function.
ORGANISM(S): Mus musculus (Mouse) 
2018-06-28 | PXD006896 | Pride
Prm 
Sort   by:  
 Page size