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TranscriptomicsSorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
In flies, small silencing RNAs are sorted between Argonaute1 (Ago1), the central protein component of the microRNA (miRNA) pathway, and Argonaute2 (Ago2), which mediates RNA interference. Extensive double-stranded characterM-bM-^@M-^Tas is found in small interfering RNAs (siRNAs)M-bM-^@M-^Tdirects d...
ORGANISM(S): Drosophila melanogaster 
2009-10-31 | E-GEOD-18806 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of MYC DNA-binding sites in Burkitt's lymphoma
Background: MYC is a transcription factor encoded by the c-MYC gene (thereafter termed MYC). MYC is key transcription factor involved in many central cellular processes including ribosomal biogenesis. MYC is overexpressed in the majority of human tumours including aggressive B-cell lymphoma especial...
ORGANISM(S): Homo sapiens 
2011-11-28 | E-GEOD-30726 | biostudies-arrayexpress
ProteomicsProteome changes in IFN-γ stimulated human macrophages in response to glycolysis or OXPHOS inhibition
Human monocytes from healthy blood donors were cultured with Macrophage colony-stimulating -factor (M-CSF) for 7-10 days, posteriorly they were stimulated with IFN-γ in media supplemented either with galactose, glucose or glucose + oligomycin. Comparisson IFN-γ with glucose supplemented media Vs. ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-17 | PXD060951 | Pride
Gbp1 cxcl10 Oxphos Metabolismo Macrophages Interferon-gamma 
TranscriptomicsRERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer
Using microarray analysis, we identified a unique ras superfamily gene, termed RERG (ras-related and estrogen-regulated growth inhibitor), whose expression was decreased or lost in a significant percentage of primary human breast tumors that show a poor clinical prognosis. Importantly, high RERG exp...
ORGANISM(S): Homo sapiens 
2005-07-23 | E-GEOD-2987 | biostudies-arrayexpress
GenomicsAn Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Gallus gallus 
2013-03-26 | E-GEOD-44690 | biostudies-arrayexpress
UnknownCamostat Mesylate Versus Lopinavir/Ritonavir in Hospitalized Patients With COVID-19-Results From a Randomized, Controlled, Open Label, Platform Trial (ACOVACT).
Not available
S-EPMC9354138 | biostudies-literature
UnknownModulating the Electronic and Solid-State Structure of Organic Semiconductors by Site-Specific Substitution: The Case of Tetrafluoropentacenes.
Not available
S-EPMC7154741 | biostudies-literature
ProteomicsIdentification of MHC-I presented porcine respiratory and re-productive syndrome virus (PRRSV) peptides reveals immu-nogenic epitopes within several non-structural proteins recog-nized by CD8+ T cells
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most relevant por-cine pathogens worldwide. Active control of the disease relies on modified live virus vaccines (MLVs), as most inactivated vaccines provide very limited protection. Neutralizing antibodies occur late in infec...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-10-14 | PXD035499 | Pride
Porcine reproductive and respiratory syndrome virus  prrsv  arteriviridae  cd8+ t cells  im-munopeptidome  epitopes  swine leukocyte antigen class i  major histocompatibility complex class i  mass spectrometry  restimulation  intracellular cytokine staining 
UnknownUV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents.
Not available
S-EPMC10511785 | biostudies-literature
ProteomicsImiquimod in human CD8+ T cells
Blood CD8 T cells from six healthy blood donors were treated with the TLR7 agonist imiquimod + IL-2 in T cell enriched medium overnight in vitro (the controls were incubated with T cell enriched medium + IL-2 only). After approx. 21 h the in solution digest protocol was started.
ORGANISM(S): Homo sapiens (Human) 
2024-04-29 | PXD038621 | Pride
Imiquimod Cd8 t cells 
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